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more general categories	information about this item
03. Biological Effects of Specific Chemicals	03. Biological Effects of Specific Chemicals
biochemical uses [CHEBI:52206] (3306)
enzyme inhibitor [CHEBI:23924] (825)	berberine [CHEBI:16118] (1)
metabolite [CHEBI:25212] (2692)
secondary metabolite [CHEBI:26619] (2225)	berberine [CHEBI:16118] (1)
biophysical uses [CHEBI:52208] (136)
membrane transport modulator [CHEBI:38632] (122)
potassium channel modulator [CHEBI:50510] (11)
potassium channel blocker [CHEBI:50509] (10)	berberine [CHEBI:16118] (1)
04. Bioactive Capabilities of Specific Chemicals	04. Bioactive Capabilities of Specific Chemicals
Oxidoreductases [EC:1] (1697)
Acting on the CH-CH group of donors [EC:1.3] (238)
With oxygen as acceptor [EC:1.3.3] (25)
Tetrahydroberberine oxidase [EC:1.3.3.8] (5)	berberine [CHEBI:16118] (1)
Acting on the CH-NH group of donors [EC:1.5] (120)
With NAD or NADP as acceptor [EC:1.5.1] (77)
Berberine reductase [EC:1.5.1.31] (5)	berberine [CHEBI:16118] (1)
Acting on X-H and Y-H to form an X-Y bond [EC:1.21] (35)
With oxygen as acceptor [EC:1.21.3] (23)
Columbamine oxidase [EC:1.21.3.2] (4)	berberine [CHEBI:16118] (1)
05. Industrial Uses	05. Industrial Uses
pharmaceutical [CHEBI:52217] (1978)
drug [CHEBI:23888] (1930)
antineoplastic agent [CHEBI:35610] (760)	berberine [CHEBI:16118] (1)
antilipemic drug [CHEBI:35679] (30)	berberine [CHEBI:16118] (1)
hypoglycemic agent [CHEBI:35526] (29)	berberine [CHEBI:16118] (1)
06. Name of Biological Source of Chemical	06. Name of Biological Source of Chemical
Plantae (1926)
Magnoliophyta (1872)
Magnoliopsida (1649)
Ranunculales (30)
Ranunculaceae (29)
Coptis (3)	Coptis japonica (3)
Hydrastis (7)	Hydrastis canadensis (7)
07. Part of Biological Source of Chemical	07. Part of Biological Source of Chemical
plant structure [PO:0009011] (1497)
multi-tissue plant structure [PO:0025496] (1114)
plant organ [PO:0009008] (970)
phyllome [PO:0006001] (351)	leaf [PO:0025034] (351)
plant axis [PO:0025004] (691)
shoot axis [PO:0025029] (271)	rhizome [PO:0004542] (88)
08. Chemical Category	08. Chemical Category
main group molecular entity [CHEBI:33579] (25650)
p-block molecular entity [CHEBI:33675] (25343)
pnictogen molecular entity [CHEBI:33302] (10027)
nitrogen molecular entity [CHEBI:51143] (7930)
organonitrogen compound [CHEBI:35352] (6705)
alkaloid [CHEBI:22315] (473)
isoquinoline alkaloid [CHEBI:24921] (120)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
carbon group molecular entity [CHEBI:33582] (23847)
organic molecular entity [CHEBI:50860] (23769)
heteroorganic entity [CHEBI:33285] (15197)
organic heterocyclic compound [CHEBI:24532] (5243)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organonitrogen compound [CHEBI:35352] (6705)
alkaloid [CHEBI:22315] (473)
isoquinoline alkaloid [CHEBI:24921] (120)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic molecule [CHEBI:72695] (11399)
organic cyclic compound [CHEBI:33832] (7633)
organic heterocyclic compound [CHEBI:24532] (5243)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
polyatomic entity [CHEBI:36357] (18777)
molecule [CHEBI:25367] (11520)
cyclic compound [CHEBI:33595] (7817)
polycyclic compound [CHEBI:33635] (4078)
heteropolycyclic compound [CHEBI:33671] (2613)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic cyclic compound [CHEBI:33832] (7633)
organic heterocyclic compound [CHEBI:24532] (5243)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
heterocyclic compound [CHEBI:5686] (5275)
organic heterocyclic compound [CHEBI:24532] (5243)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
heteropolycyclic compound [CHEBI:33671] (2613)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic molecule [CHEBI:72695] (11399)
organic cyclic compound [CHEBI:33832] (7633)
organic heterocyclic compound [CHEBI:24532] (5243)
organonitrogen heterocyclic compound [CHEBI:38101] (3202)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
organic heteropolycyclic compound [CHEBI:38166] (2613)
organic heterotetracyclic compound [CHEBI:38163] (128)
dibenzoquinolizine [CHEBI:38512] (14)
berberine alkaloid [CHEBI:22754] (14)	berberine [CHEBI:16118] (1)
09. Chemical Capabilities	09. Chemical Capabilities
antioxidant [CHEBI:22586] (199)	berberine [CHEBI:16118] (1)
ChEBI Compound Accession Identifier:	[CHEBI:16118]
ChEBI Compound Description:	null
ChEBI Compound Identification Number:	16118
ChEBI InChI Value:	InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1
ChEBI InChIKey Value:	YBHILYKTIRIUTE-UHFFFAOYSA-N
ChEBI Compound Name:	berberine
ChEBI SMILES Value:	COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC
ChEBI Substance ID:	8145003
ChEBI URL:	ChEBI:16118
ChemSpider ID:	NS
Ontomatica Chemical Accession Key (OnChAKey):	YBHILYKTIRIUTE_UHFFFAOYSA_N_000_000000
PubChem Compound ID:	2353