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cyclothiazide
3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.


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05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antihypertensive agent [CHEBI:35674] (104) 
 cyclothiazide [CHEBI:31448] (1)
 diuretic [CHEBI:35498] (18) 
 cyclothiazide [CHEBI:31448] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 sulfur molecular entity [CHEBI:26835] (1541) 
 organosulfur compound [CHEBI:33261] (1005) 
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
 organosulfur heterocyclic compound [CHEBI:38106] (367) 
 thiazide [CHEBI:50264] (6) 
 benzothiadiazine [CHEBI:50265] (6) 
 cyclothiazide [CHEBI:31448] (1)
ChEBI Compound Accession Identifier  [CHEBI:31448]
ChEBI Compound Description  3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
ChEBI Compound Identification Number  31448
ChEBI InChI Value  InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)
ChEBI InChIKey Value  BOCUKUHCLICSIY-UHFFFAOYSA-N
ChEBI Compound Name  cyclothiazide
ChEBI SMILES Value  NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C2CC3CC2C=C3)cc1Cl
ChEBI Substance ID  96079565
ChEBI URL  ChEBI:31448
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  BOCUKUHCLICSIY_UHFFFAOYSA_N_000_000000
PubChem Compound ID  2910