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enalaprilat dihydrate
The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > angiotensin-converting enzyme inhibitor [CHEBI:35457] > enalaprilat dihydrate [CHEBI:59877]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 angiotensin-converting enzyme inhibitor [CHEBI:35457] (14) 
 enalaprilat dihydrate [CHEBI:59877] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antihypertensive agent [CHEBI:35674] (104) 
 enalaprilat dihydrate [CHEBI:59877] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 addition compound [CHEBI:35504] (113) 
 hydrate [CHEBI:35505] (111) 
 enalaprilat dihydrate [CHEBI:59877] (1)
ChEBI Compound Accession Identifier  [CHEBI:59877]
ChEBI Compound Description  The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.
ChEBI Compound Identification Number  59877
ChEBI InChI Value  "InChI=1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1"
ChEBI InChIKey Value  MZYVOFLIPYDBGD-MLZQUWKJSA-N
ChEBI Compound Name  enalaprilat dihydrate
ChEBI SMILES Value  O.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
ChEBI Substance ID  99319603
ChEBI URL  ChEBI:59877
ChemSpider ID  5292946
Ontomatica Chemical Accession Key (OnChAKey)  MZYVOFLIPYDBGD_MLZQUWKJSA_N_000_000000
PubChem Compound ID  6917719