Item 1 of 1 (back to results) entecavir hydrate The monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > reverse transcriptase inhibitor [CHEBI:59897] > entecavir hydrate [CHEBI:59902] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   reverse transcriptase inhibitor [CHEBI:59897] (5)   entecavir hydrate [CHEBI:59902] (1)  antimicrobial agent [CHEBI:33281] (927)   antiviral agent [CHEBI:22587] (216)   antiviral drug [CHEBI:36044] (50)   entecavir hydrate [CHEBI:59902] (1) 08. Chemical Category  08. Chemical Category  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   addition compound [CHEBI:35504] (113)   hydrate [CHEBI:35505] (111)   entecavir hydrate [CHEBI:59902] (1) ChEBI Compound Accession Identifier:   [CHEBI:59902] ChEBI Compound Description:   The monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. ChEBI Compound Identification Number:   59902 ChEBI InChI Value:   "InChI=1S/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/m0./s1" ChEBI InChIKey Value:   YXPVEXCTPGULBZ-WQYNNSOESA-N ChEBI Compound Name:   entecavir hydrate ChEBI SMILES Value:   O.Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)C1=C ChEBI Substance ID:   99319526 ChEBI URL:   ChEBI:59902 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   YXPVEXCTPGULBZ_WQYNNSOESA_N_000_000000 PubChem Compound ID:   16052026