Item 1 of 1 (back to results) depudecin A polyketide obtained from the fungus Alternaria brassicicola and having a highly unusual structure of an 11-carbon chain containing two epoxides and six stereogenic centres. It is an inhibitor of histone deacetylase (HDAC) both in vivo and in vitro and also exhibits anti-angiogenic activity.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > histone deacetylase inhibitor [CHEBI:61115] > depudecin [CHEBI:64143] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   histone deacetylase inhibitor [CHEBI:61115] (11)   depudecin [CHEBI:64143] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   organooxygen compound [CHEBI:36963] (11352)   polyketide [CHEBI:26188] (172)   depudecin [CHEBI:64143] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   polyketide [CHEBI:26188] (172)   depudecin [CHEBI:64143] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   polyketide [CHEBI:26188] (172)   depudecin [CHEBI:64143] (1) ChEBI Compound Accession Identifier:   [CHEBI:64143] ChEBI Compound Description:   A polyketide obtained from the fungus Alternaria brassicicola and having a highly unusual structure of an 11-carbon chain containing two epoxides and six stereogenic centres. It is an inhibitor of histone deacetylase (HDAC) both in vivo and in vitro and also exhibits anti-angiogenic activity. ChEBI Compound Identification Number:   64143 ChEBI InChI Value:   InChI=1S/C11H16O4/c1-3-7(13)11-9(15-11)5-4-8-10(14-8)6(2)12/h3-13H,1H2,2H3/b5-4+/t6-,7-,8+,9+,10+,11+/m1/s1 ChEBI InChIKey Value:   DLVJMFOLJOOWFS-INMLLLKOSA-N ChEBI Compound Name:   depudecin ChEBI SMILES Value:   [H][C@]1(O[C@H]1\C=C\[C@@H]1O[C@@]1([H])[C@H](O)C=C)[C@@H](C)O ChEBI Substance ID:   135610587 ChEBI URL:   ChEBI:64143 ChemSpider ID:   21169370 Ontomatica Chemical Accession Key (OnChAKey):   DLVJMFOLJOOWFS_INMLLLKOSA_N_000_000000 PubChem Compound ID:   16219259