Item 1 of 1 (back to results) 5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen A member of the class of psoralens that is psoralen substituted by a methoxy group at position 4 and a [(2R)-3-butoxy-2-hydroxy-3-methylbutyl]oxy group at position 9. Isolated from the roots of Angelica dahurica, it exhibits inhibitory activity against COX-2 and 5-lipooxygenase.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > cyclooxygenase inhibitor [CHEBI:35544] > cyclooxygenase 2 inhibitor [CHEBI:50629] > 5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   lipoxygenase inhibitor [CHEBI:35856] (23)   arachidonate 5-lipoxygenase inhibitor [CHEBI:64964] (9)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  cyclooxygenase inhibitor [CHEBI:35544] (58)   cyclooxygenase 2 inhibitor [CHEBI:50629] (37)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Plantae (1926)   Magnoliophyta (1872)   Magnoliopsida (1649)   Apiales (90)   Apiaceae (42)   Angelica (9)   Angelica dahurica (4) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  plant structure [PO:0009011] (1497)   multi-tissue plant structure [PO:0025496] (1114)   plant organ [PO:0009008] (970)   plant axis [PO:0025004] (691)   root [PO:0009005] (486) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   polycyclic compound [CHEBI:33635] (4078)   heteropolycyclic compound [CHEBI:33671] (2613)   heterotricyclic compound [CHEBI:36688] (541)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  aromatic compound [CHEBI:33655] (3799)   organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  heteropolycyclic compound [CHEBI:33671] (2613)   heterotricyclic compound [CHEBI:36688] (541)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   furochromene [CHEBI:39432] (37)   furanocoumarin [CHEBI:24128] (35)   psoralens [CHEBI:26369] (12)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen [CHEBI:66697] (1) ChEBI Compound Accession Identifier:   [CHEBI:66697] ChEBI Compound Description:   A member of the class of psoralens that is psoralen substituted by a methoxy group at position 4 and a [(2R)-3-butoxy-2-hydroxy-3-methylbutyl]oxy group at position 9. Isolated from the roots of Angelica dahurica, it exhibits inhibitory activity against COX-2 and 5-lipooxygenase. ChEBI Compound Identification Number:   66697 ChEBI InChI Value:   InChI=1S/C21H26O7/c1-5-6-10-27-21(2,3)15(22)12-26-20-18-14(9-11-25-18)17(24-4)13-7-8-16(23)28-19(13)20/h7-9,11,15,22H,5-6,10,12H2,1-4H3/t15-/m1/s1 ChEBI InChIKey Value:   HYFWQORTIZQRLZ-OAHLLOKOSA-N ChEBI Compound Name:   5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen ChEBI SMILES Value:   CCCCOC(C)(C)[C@H](O)COc1c2occc2c(OC)c2ccc(=O)oc12 ChEBI Substance ID:   160710682 ChEBI URL:   ChEBI:66697 ChemSpider ID:   28639025 Ontomatica Chemical Accession Key (OnChAKey):   HYFWQORTIZQRLZ_OAHLLOKOSA_N_000_000000 PubChem Compound ID:   70697917