Item 1 of 1 (back to results) 8alpha-19-dihydroxylabd-13E-ene-15-oic acid A labdane diterpenoid that is labdane with a double bond at position 13 and is substituted by hydroxy groups at positions 8alpha and 19 and a carboxy group at position 15. Isolated from the aerial parts of Crassocephalum mannii, it exhibits inhibitory activity towards cyclooxygenases (COX-1 and COX-2).

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > cyclooxygenase inhibitor [CHEBI:35544] > cyclooxygenase 1 inhibitor [CHEBI:50630] > 8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   cyclooxygenase inhibitor [CHEBI:35544] (58)   cyclooxygenase 2 inhibitor [CHEBI:50629] (37)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  cyclooxygenase 1 inhibitor [CHEBI:50630] (15)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic hydroxy compound [CHEBI:33822] (3050)   polyol [CHEBI:26191] (437)   diol [CHEBI:23824] (172)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic hydroxy compound [CHEBI:33822] (3050)   polyol [CHEBI:26191] (437)   diol [CHEBI:23824] (172)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   labdane diterpenoid [CHEBI:36770] (21)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   labdane diterpenoid [CHEBI:36770] (21)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  heteroorganic entity [CHEBI:33285] (15197)   organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic hydroxy compound [CHEBI:33822] (3050)   polyol [CHEBI:26191] (437)   diol [CHEBI:23824] (172)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic acid [CHEBI:64709] (3008)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   monocarboxylic acid [CHEBI:25384] (1620)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1)  organic hydroxy compound [CHEBI:33822] (3050)   polyol [CHEBI:26191] (437)   diol [CHEBI:23824] (172)   8alpha-19-dihydroxylabd-13E-ene-15-oic acid [CHEBI:65789] (1) ChEBI Compound Accession Identifier:   [CHEBI:65789] ChEBI Compound Description:   A labdane diterpenoid that is labdane with a double bond at position 13 and is substituted by hydroxy groups at positions 8alpha and 19 and a carboxy group at position 15. Isolated from the aerial parts of Crassocephalum mannii, it exhibits inhibitory activity towards cyclooxygenases (COX-1 and COX-2). ChEBI Compound Identification Number:   65789 ChEBI InChI Value:   InChI=1S/C20H34O4/c1-14(12-17(22)23)6-7-16-19(3)10-5-9-18(2,13-21)15(19)8-11-20(16,4)24/h12,15-16,21,24H,5-11,13H2,1-4H3,(H,22,23)/b14-12+/t15-,16+,18-,19-,20+/m0/s1 ChEBI InChIKey Value:   IYSBWLRXTOIYFZ-KBLZDMJYSA-N ChEBI Compound Name:   8alpha-19-dihydroxylabd-13E-ene-15-oic acid ChEBI SMILES Value:   [H][C@@]12CC[C@@](C)(O)[C@H](CC\C(C)=C\C(O)=O)[C@@]1(C)CCC[C@@]2(C)CO ChEBI Substance ID:   160709513 ChEBI URL:   ChEBI:65789 ChemSpider ID:   24713077 Ontomatica Chemical Accession Key (OnChAKey):   IYSBWLRXTOIYFZ_KBLZDMJYSA_N_000_000000 PubChem Compound ID:   24899923