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5,5'-dibutoxy-2,2'-bifuran
A ring assembly that consists of 2,2'-bifuran substituted by butoxy groups at positions 5 and 5' respectively. It is isolated from the aerial parts of Chrysanthemum coronarium and acts as an inhibitor of human AcylCoA:cholesterol acyltransferase hACAT-1 and hACAT-2.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > acyl-CoA:cholesterol acyltransferase inhibitor [CHEBI:64696] > 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 acyl-CoA:cholesterol acyltransferase inhibitor [CHEBI:64696] (11) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 monocyclic compound [CHEBI:33661] (2007) 
 heteromonocyclic compound [CHEBI:33670] (2004) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 ring assembly [CHEBI:36820] (165) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 heteromonocyclic compound [CHEBI:33670] (2004) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
 oxacycle [CHEBI:38104] (2002) 
 furans [CHEBI:24129] (114) 
 5,5'-dibutoxy-2,2'-bifuran [CHEBI:65763] (1)
ChEBI Compound Accession Identifier  [CHEBI:65763]
ChEBI Compound Description  A ring assembly that consists of 2,2'-bifuran substituted by butoxy groups at positions 5 and 5' respectively. It is isolated from the aerial parts of Chrysanthemum coronarium and acts as an inhibitor of human AcylCoA:cholesterol acyltransferase hACAT-1 and hACAT-2.
ChEBI Compound Identification Number  65763
ChEBI InChI Value  InChI=1S/C16H22O4/c1-3-5-11-17-15-9-7-13(19-15)14-8-10-16(20-14)18-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
ChEBI InChIKey Value  BQFASOONPNRMGH-UHFFFAOYSA-N
ChEBI Compound Name  5,5'-dibutoxy-2,2'-bifuran
ChEBI SMILES Value  CCCCOc1ccc(o1)-c1ccc(OCCCC)o1
ChEBI Substance ID  160709553
ChEBI URL  ChEBI:65763
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  BQFASOONPNRMGH_UHFFFAOYSA_N_000_000000
PubChem Compound ID  70697742