Item 1 of 1 (back to results) TMC-1C A polyene antibiotic that is hexa-1,3,5-triene substituted at position 1 by a cyclohex-1-en-1-yl group substituted by a (4,6-dimethyldeca-2,4-dienoyl)amino group, hydroxy groups and oxo group at positions 1, 3, 4 and 6 respectively and at position 6 by a N-(2-hydroxy-5-oxocyclopent-1-en-1-yl)formamyl group. It is an antitumour antibiotic isolated from Streptomyces sp. A-230.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > secondary metabolite [CHEBI:26619] > TMC-1C [CHEBI:66236] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   TMC-1C [CHEBI:66236] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   TMC-1C [CHEBI:66236] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Archaea, Cyanobacteria and Bacteria (302)   Eubacteria (239)   Firmicutes (214)   Actinobacteria (204)   Actinobacteridae (204)   Actinomycetales (204)   Streptomycetaceae (160)   Streptomyces (157) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  unspecified structure [PO:0000004] (703) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   polyene antibiotic [CHEBI:26177] (10)   TMC-1C [CHEBI:66236] (1)  alcohol [CHEBI:30879] (1371)   tertiary alcohol [CHEBI:26878] (183)   TMC-1C [CHEBI:66236] (1)  secondary alcohol [CHEBI:35681] (342)   TMC-1C [CHEBI:66236] (1)  enol [CHEBI:33823] (52)   TMC-1C [CHEBI:66236] (1)  p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   amide [CHEBI:32988] (1863)   primary amide [CHEBI:33256] (1586)   carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   polyene antibiotic [CHEBI:26177] (10)   TMC-1C [CHEBI:66236] (1)  alcohol [CHEBI:30879] (1371)   tertiary alcohol [CHEBI:26878] (183)   TMC-1C [CHEBI:66236] (1)  secondary alcohol [CHEBI:35681] (342)   TMC-1C [CHEBI:66236] (1)  enol [CHEBI:33823] (52)   TMC-1C [CHEBI:66236] (1)  organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   TMC-1C [CHEBI:66236] (1)  alpha,beta-unsaturated ketone [CHEBI:51721] (238)   enone [CHEBI:51689] (233)   TMC-1C [CHEBI:66236] (1)  carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   TMC-1C [CHEBI:66236] (1)  alpha,beta-unsaturated ketone [CHEBI:51721] (238)   enone [CHEBI:51689] (233)   TMC-1C [CHEBI:66236] (1)  carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   TMC-1C [CHEBI:66236] (1)  alpha,beta-unsaturated ketone [CHEBI:51721] (238)   enone [CHEBI:51689] (233)   TMC-1C [CHEBI:66236] (1)  carboxamide [CHEBI:37622] (1381)   TMC-1C [CHEBI:66236] (1)  organic hydroxy compound [CHEBI:33822] (3050)   polyene antibiotic [CHEBI:26177] (10)   TMC-1C [CHEBI:66236] (1)  alcohol [CHEBI:30879] (1371)   tertiary alcohol [CHEBI:26878] (183)   TMC-1C [CHEBI:66236] (1)  secondary alcohol [CHEBI:35681] (342)   TMC-1C [CHEBI:66236] (1)  enol [CHEBI:33823] (52)   TMC-1C [CHEBI:66236] (1)  organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   TMC-1C [CHEBI:66236] (1)  alpha,beta-unsaturated ketone [CHEBI:51721] (238)   enone [CHEBI:51689] (233)   TMC-1C [CHEBI:66236] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   TMC-1C [CHEBI:66236] (1)  alpha,beta-unsaturated ketone [CHEBI:51721] (238)   enone [CHEBI:51689] (233)   TMC-1C [CHEBI:66236] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   polyene antibiotic [CHEBI:26177] (10)   TMC-1C [CHEBI:66236] (1)  alcohol [CHEBI:30879] (1371)   tertiary alcohol [CHEBI:26878] (183)   TMC-1C [CHEBI:66236] (1)  secondary alcohol [CHEBI:35681] (342)   TMC-1C [CHEBI:66236] (1)  enol [CHEBI:33823] (52)   TMC-1C [CHEBI:66236] (1) ChEBI Compound Accession Identifier:   [CHEBI:66236] ChEBI Compound Description:   A polyene antibiotic that is hexa-1,3,5-triene substituted at position 1 by a cyclohex-1-en-1-yl group substituted by a (4,6-dimethyldeca-2,4-dienoyl)amino group, hydroxy groups and oxo group at positions 1, 3, 4 and 6 respectively and at position 6 by a N-(2-hydroxy-5-oxocyclopent-1-en-1-yl)formamyl group. It is an antitumour antibiotic isolated from Streptomyces sp. A-230. ChEBI Compound Identification Number:   66236 ChEBI InChI Value:   InChI=1S/C30H38N2O7/c1-4-5-10-20(2)17-21(3)12-15-28(38)31-22-19-30(39,26(36)18-25(22)35)16-9-7-6-8-11-27(37)32-29-23(33)13-14-24(29)34/h6-9,11-12,15-17,19-20,26,33,36,39H,4-5,10,13-14,18H2,1-3H3,(H,31,38)(H,32,37)/b7-6+,11-8+,15-12+,16-9+,21-17+/t20?,26-,30+/m1/s1 ChEBI InChIKey Value:   WDPVYGCEBGDANZ-CXLBDHTJSA-N ChEBI Compound Name:   TMC-1C ChEBI SMILES Value:   CCCCC(C)\C=C(C)\C=C\C(=O)NC1=C[C@@](O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)[C@H](O)CC1=O ChEBI Substance ID:   160645222 ChEBI URL:   ChEBI:66236 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   WDPVYGCEBGDANZ_CXLBDHTJSA_N_000_000000 PubChem Compound ID:   10030158