Item 1 of 1 (back to results) phosphatoquinone A A naphthoquinone that is 1a-methyl-1a,7a-dihydronaphtho[2,3-b]oxirene-2,7-dione substituted at position 7a by a [(2E)-3,7-dimethylocta-2,6-dien-1-yl] group and at positions 3 and 5 by hydroxy groups. It is isolated from the culture broth of Streptomyces sp.TC-0363 and exhibits inhibitory activity against the enzyme protein tyrosine phosphatase.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > secondary metabolite [CHEBI:26619] > phosphatoquinone A [CHEBI:66751] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   protein tyrosine phosphatase inhibitor [CHEBI:35608] (3)   phosphatoquinone A [CHEBI:66751] (1)  metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   phosphatoquinone A [CHEBI:66751] (1)  antimicrobial agent [CHEBI:33281] (927)   antibiotic [CHEBI:22582] (193)   phosphatoquinone A [CHEBI:66751] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Archaea, Cyanobacteria and Bacteria (302)   Eubacteria (239)   Firmicutes (214)   Actinobacteria (204)   Actinobacteridae (204)   Actinomycetales (204)   Streptomycetaceae (160)   Streptomyces (157) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  unspecified structure [PO:0000004] (703) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organic hydroxy compound [CHEBI:33822] (3050)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organic aromatic compound [CHEBI:33659] (3593)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   aromatic compound [CHEBI:33655] (3799)   organic aromatic compound [CHEBI:33659] (3593)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organic aromatic compound [CHEBI:33659] (3593)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ether [CHEBI:37407] (314)   epoxide [CHEBI:32955] (145)   phosphatoquinone A [CHEBI:66751] (1)  organic aromatic compound [CHEBI:33659] (3593)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   naphthoquinone [CHEBI:25481] (25)   phosphatoquinone A [CHEBI:66751] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   phenols [CHEBI:33853] (868)   phosphatoquinone A [CHEBI:66751] (1) ChEBI Compound Accession Identifier:   [CHEBI:66751] ChEBI Compound Description:   A naphthoquinone that is 1a-methyl-1a,7a-dihydronaphtho[2,3-b]oxirene-2,7-dione substituted at position 7a by a [(2E)-3,7-dimethylocta-2,6-dien-1-yl] group and at positions 3 and 5 by hydroxy groups. It is isolated from the culture broth of Streptomyces sp.TC-0363 and exhibits inhibitory activity against the enzyme protein tyrosine phosphatase. ChEBI Compound Identification Number:   66751 ChEBI InChI Value:   InChI=1S/C21H24O5/c1-12(2)6-5-7-13(3)8-9-21-18(24)15-10-14(22)11-16(23)17(15)19(25)20(21,4)26-21/h6,8,10-11,22-23H,5,7,9H2,1-4H3/b13-8+/t20-,21+/m0/s1 ChEBI InChIKey Value:   QTORDDSSLVGNHO-BGTMZHHNSA-N ChEBI Compound Name:   phosphatoquinone A ChEBI SMILES Value:   CC(C)=CCC\C(C)=C\C[C@]12O[C@@]1(C)C(=O)c1c(O)cc(O)cc1C2=O ChEBI Substance ID:   160645459 ChEBI URL:   ChEBI:66751 ChemSpider ID:   8648865 Ontomatica Chemical Accession Key (OnChAKey):   QTORDDSSLVGNHO_BGTMZHHNSA_N_000_000000 PubChem Compound ID:   10473454