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7-oxo-3,8,9-trihydroxy staurosporine
A indolocarbazole alkaloid that is staurosporine substituted by hydroxy groups at positions 3, 8 and 9 and an oxo group at position 7. Isolated from Cystodytes solitus, it exhibits cytotoxic activity.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > secondary metabolite [CHEBI:26619] > 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antineoplastic agent [CHEBI:35610] (760) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 alkaloid [CHEBI:22315] (473) 
 indole alkaloid [CHEBI:38958] (144) 
 indolocarbazole alkaloid [CHEBI:37697] (4) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 alkaloid [CHEBI:22315] (473) 
 indole alkaloid [CHEBI:38958] (144) 
 indolocarbazole alkaloid [CHEBI:37697] (4) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 polycyclic compound [CHEBI:33635] (4078) 
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 aromatic compound [CHEBI:33655] (3799) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterooctacyclic compound [CHEBI:38165] (5) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 indolocarbazole [CHEBI:51915] (9) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 polyphenol [CHEBI:26195] (189) 
 7-oxo-3,8,9-trihydroxy staurosporine [CHEBI:66839] (1)
ChEBI Compound Accession Identifier  [CHEBI:66839]
ChEBI Compound Description  A indolocarbazole alkaloid that is staurosporine substituted by hydroxy groups at positions 3, 8 and 9 and an oxo group at position 7. Isolated from Cystodytes solitus, it exhibits cytotoxic activity.
ChEBI Compound Identification Number  66839
ChEBI InChI Value  InChI=1S/C28H24N4O7/c1-28-25(38-3)12(29-2)9-16(39-28)31-13-5-4-10(33)8-11(13)17-20-21(27(37)30-26(20)36)19-18-14(6-7-15(34)24(18)35)32(28)23(19)22(17)31/h4-8,12,16,25,29,33-35H,9H2,1-3H3,(H,30,36,37)/t12-,16-,25-,28+/m1/s1
ChEBI InChIKey Value  VDHMIDRUYQWJMP-WSDGDUIDSA-N
ChEBI Compound Name  7-oxo-3,8,9-trihydroxy staurosporine
ChEBI SMILES Value  [H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)n1c3ccc(O)c(O)c3c3c4C(=O)NC(=O)c4c4c5cc(O)ccc5n2c4c13
ChEBI Substance ID  160710504
ChEBI URL  ChEBI:66839
ChemSpider ID  24703356
Ontomatica Chemical Accession Key (OnChAKey)  VDHMIDRUYQWJMP_WSDGDUIDSA_N_000_000000
PubChem Compound ID  24899660