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fosmidomycin
Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > fosmidomycin [CHEBI:443725]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 fosmidomycin [CHEBI:443725] (1)
 antimicrobial agent [CHEBI:33281] (927) 
 antibiotic [CHEBI:22582] (193) 
 fosmidomycin [CHEBI:443725] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 phosphorus molecular entity [CHEBI:26082] (2769) 
 phosphorus oxoacids and derivatives [CHEBI:36360] (2691) 
 phosphonic acids [CHEBI:26069] (25) 
 fosmidomycin [CHEBI:443725] (1)
 nitrogen molecular entity [CHEBI:51143] (7930) 
 amide [CHEBI:32988] (1863) 
 primary amide [CHEBI:33256] (1586) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 hydroxamic acid [CHEBI:24650] (25) 
 fosmidomycin [CHEBI:443725] (1)
ChEBI Compound Accession Identifier  [CHEBI:443725]
ChEBI Compound Description  Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
ChEBI Compound Identification Number  443725
ChEBI InChI Value  InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10)
ChEBI InChIKey Value  GJXWDTUCERCKIX-UHFFFAOYSA-N
ChEBI Compound Name  fosmidomycin
ChEBI SMILES Value  ON(CCCP(O)(O)=O)C=O
ChEBI Substance ID  87351364
ChEBI URL  ChEBI:443725
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  GJXWDTUCERCKIX_UHFFFAOYSA_N_000_000000
PubChem Compound ID  572