Item 1 of 1 (back to results) chaetominine An organic heterotetracyclic compound that consists of 4,5,5a,9c-tetrahydro-3H-2a,9b-diazacyclopenta[jk]fluorene-1,3(2H)-dione substituted by a hydroxy group at position 5, a methyl group at position 2 and a 4-oxoquinazolin-3(4H)-yl group at position 4 (the 2S,4R,5aS,9cS stereoisomer). It is a cytotoxic alkaloid isolated from the endophytic fungus Chaetomium.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > secondary metabolite [CHEBI:26619] > chaetominine [CHEBI:65610] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   chaetominine [CHEBI:65610] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Fungi, Yeasts, Molds and Mildews (348)   Dikarya (97)   Ascomycota (82)   Pezizomycotina (82)   Sordariomycetes (72)   Sordariomycetidae (30)   Sordariales (30)   Chaetomiaceae (28)   Chaetomium (28) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  unspecified structure [PO:0000004] (703) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   amide [CHEBI:32988] (1863)   cyclic amide [CHEBI:3990] (252)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organonitrogen compound [CHEBI:35352] (6705)   alkaloid [CHEBI:22315] (473)   indole alkaloid [CHEBI:38958] (144)   chaetominine [CHEBI:65610] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  organonitrogen compound [CHEBI:35352] (6705)   alkaloid [CHEBI:22315] (473)   indole alkaloid [CHEBI:38958] (144)   chaetominine [CHEBI:65610] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   polycyclic compound [CHEBI:33635] (4078)   heteropolycyclic compound [CHEBI:33671] (2613)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  bicyclic compound [CHEBI:33636] (1511)   heterobicyclic compound [CHEBI:33672] (1315)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  heteropolycyclic compound [CHEBI:33671] (2613)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1)  heterobicyclic compound [CHEBI:33672] (1315)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   lactam [CHEBI:24995] (252)   chaetominine [CHEBI:65610] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinazolines [CHEBI:38530] (18)   chaetominine [CHEBI:65610] (1)  organic heterotetracyclic compound [CHEBI:38163] (128)   chaetominine [CHEBI:65610] (1) ChEBI Compound Accession Identifier:   [CHEBI:65610] ChEBI Compound Description:   An organic heterotetracyclic compound that consists of 4,5,5a,9c-tetrahydro-3H-2a,9b-diazacyclopenta[jk]fluorene-1,3(2H)-dione substituted by a hydroxy group at position 5, a methyl group at position 2 and a 4-oxoquinazolin-3(4H)-yl group at position 4 (the 2S,4R,5aS,9cS stereoisomer). It is a cytotoxic alkaloid isolated from the endophytic fungus Chaetomium. ChEBI Compound Identification Number:   65610 ChEBI InChI Value:   InChI=1S/C22H18N4O4/c1-12-18(27)26-16-9-5-3-7-14(16)22(30)10-17(20(29)25(12)21(22)26)24-11-23-15-8-4-2-6-13(15)19(24)28/h2-9,11-12,17,21,30H,10H2,1H3/t12-,17+,21-,22-/m0/s1 ChEBI InChIKey Value:   GEURDGODABUDHB-TYTLQBBQSA-N ChEBI Compound Name:   chaetominine ChEBI SMILES Value:   [H][C@]12N3[C@@H](C)C(=O)N1c1ccccc1[C@@]2(O)C[C@H](C3=O)n1cnc2ccccc2c1=O ChEBI Substance ID:   160645207 ChEBI URL:   ChEBI:65610 ChemSpider ID:   17253564 Ontomatica Chemical Accession Key (OnChAKey):   GEURDGODABUDHB_TYTLQBBQSA_N_000_000000 PubChem Compound ID:   16095273