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Ac-Asp-Glu-Val-Asp-H
A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > protease inhibitor [CHEBI:37670] > Ac-Asp-Glu-Val-Asp-H [CHEBI:59385]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 protease inhibitor [CHEBI:37670] (37) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 amide [CHEBI:32988] (1863) 
 primary amide [CHEBI:33256] (1586) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 tetrapeptide [CHEBI:48030] (94) 
 Ac-Asp-Glu-Val-Asp-H [CHEBI:59385] (1)
ChEBI Compound Accession Identifier  [CHEBI:59385]
ChEBI Compound Description  A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.
ChEBI Compound Identification Number  59385
ChEBI InChI Value  InChI=1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)/t11-,12-,13-,17-/m0/s1
ChEBI InChIKey Value  UMBVAPCONCILTL-MRHIQRDNSA-N
ChEBI Compound Name  Ac-Asp-Glu-Val-Asp-H
ChEBI SMILES Value  [H]C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(C)C
ChEBI Substance ID  93581455
ChEBI URL  ChEBI:59385
ChemSpider ID  559351
Ontomatica Chemical Accession Key (OnChAKey)  UMBVAPCONCILTL_MRHIQRDNSA_N_000_000000
PubChem Compound ID  644345