Item 1 of 1 (back to results) pemetrexed disodium An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > antimetabolite [CHEBI:35221] > pemetrexed disodium [CHEBI:63722] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   dihydrofolate reductase inhibitor [CHEBI:50683] (7)   pemetrexed disodium [CHEBI:63722] (1)  thymidylate synthase inhibitor [CHEBI:63720] (3)   pemetrexed disodium [CHEBI:63722] (1)  glycinamide ribonucleotide formyltransferase inhibitor [CHEBI:63721] (3)   pemetrexed disodium [CHEBI:63722] (1)  antimetabolite [CHEBI:35221] (34)   pemetrexed disodium [CHEBI:63722] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   pemetrexed disodium [CHEBI:63722] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   alkali metal molecular entity [CHEBI:33296] (279)   sodium molecular entity [CHEBI:26712] (216)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium [CHEBI:63722] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium [CHEBI:63722] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium [CHEBI:63722] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium [CHEBI:63722] (1) ChEBI Compound Accession Identifier:   [CHEBI:63722] ChEBI Compound Description:   An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). ChEBI Compound Identification Number:   63722 ChEBI InChI Value:   "InChI=1S/C20H21N5O6.2Na/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;/q;2*+1/p-2/t13-;;/m0../s1" ChEBI InChIKey Value:   NYDXNILOWQXUOF-GXKRWWSZSA-L ChEBI Compound Name:   pemetrexed disodium ChEBI SMILES Value:   [Na+].[Na+].Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1 ChEBI Substance ID:   135610834 ChEBI URL:   ChEBI:63722 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   NYDXNILOWQXUOF_GXKRWWSZSA_L_000_000000 PubChem Compound ID:   6918197