Item 1 of 1 (back to results) encainide 4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market.

Current search: 03. Biological Effects of Specific Chemicals: biophysical uses [CHEBI:52208] > membrane transport modulator [CHEBI:38632] > sodium channel modulator [CHEBI:39000] > sodium channel blocker [CHEBI:38633] > encainide [CHEBI:4788] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biophysical uses [CHEBI:52208] (136)   membrane transport modulator [CHEBI:38632] (122)   sodium channel modulator [CHEBI:39000] (43)   sodium channel blocker [CHEBI:38633] (10)   encainide [CHEBI:4788] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   cardiovascular drug [CHEBI:35554] (162)   anti-arrhythmia drug [CHEBI:38070] (56)   encainide [CHEBI:4788] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   amide [CHEBI:32988] (1863)   primary amide [CHEBI:33256] (1586)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   monocarboxylic acid amide [CHEBI:29347] (257)   arenecarboxamide [CHEBI:22645] (45)   benzamides [CHEBI:22702] (45)   encainide [CHEBI:4788] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   monocyclic compound [CHEBI:33661] (2007)   heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   piperidines [CHEBI:26151] (143)   encainide [CHEBI:4788] (1) ChEBI Compound Accession Identifier:   [CHEBI:4788] ChEBI Compound Description:   4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. ChEBI Compound Identification Number:   4788 ChEBI InChI Value:   InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25) ChEBI InChIKey Value:   PJWPNDMDCLXCOM-UHFFFAOYSA-N ChEBI Compound Name:   encainide ChEBI SMILES Value:   COc1ccc(cc1)C(=O)Nc1ccccc1CCC1CCCCN1C ChEBI Substance ID:   99313642 ChEBI URL:   ChEBI:4788 ChemSpider ID:   43697 Ontomatica Chemical Accession Key (OnChAKey):   PJWPNDMDCLXCOM_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   48041