Item 1 of 1 (back to results) topiramate A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.

Current search: 03. Biological Effects of Specific Chemicals: biophysical uses [CHEBI:52208] > membrane transport modulator [CHEBI:38632] > sodium channel modulator [CHEBI:39000] > sodium channel blocker [CHEBI:38633] > topiramate [CHEBI:63631] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biophysical uses [CHEBI:52208] (136)   membrane transport modulator [CHEBI:38632] (122)   sodium channel modulator [CHEBI:39000] (43)   sodium channel blocker [CHEBI:38633] (10)   topiramate [CHEBI:63631] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   central nervous system drug [CHEBI:35470] (217)   central nervous system depressant [CHEBI:35488] (90)   anticonvulsant [CHEBI:35623] (39)   topiramate [CHEBI:63631] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   organooxygen compound [CHEBI:36963] (11352)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  acetal [CHEBI:59769] (62)   ketal [CHEBI:59777] (29)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  carbohydrate derivative [CHEBI:63299] (2582)   monosaccharide derivative [CHEBI:63367] (720)   hexose derivative [CHEBI:63385] (67)   ketohexose derivative [CHEBI:63391] (3)   topiramate [CHEBI:63631] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  acetal [CHEBI:59769] (62)   ketal [CHEBI:59777] (29)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  carbohydrate derivative [CHEBI:63299] (2582)   monosaccharide derivative [CHEBI:63367] (720)   hexose derivative [CHEBI:63385] (67)   ketohexose derivative [CHEBI:63391] (3)   topiramate [CHEBI:63631] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  acetal [CHEBI:59769] (62)   ketal [CHEBI:59777] (29)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  carbohydrate derivative [CHEBI:63299] (2582)   monosaccharide derivative [CHEBI:63367] (720)   hexose derivative [CHEBI:63385] (67)   ketohexose derivative [CHEBI:63391] (3)   topiramate [CHEBI:63631] (1)  ester [CHEBI:35701] (3370)   sulfamate ester [CHEBI:48199] (1)   topiramate [CHEBI:63631] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   oxacycle [CHEBI:38104] (2002)   cyclic ketal [CHEBI:59779] (29)   topiramate [CHEBI:63631] (1) ChEBI Compound Accession Identifier:   [CHEBI:63631] ChEBI Compound Description:   A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. ChEBI Compound Identification Number:   63631 ChEBI InChI Value:   InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 ChEBI InChIKey Value:   KJADKKWYZYXHBB-XBWDGYHZSA-N ChEBI Compound Name:   topiramate ChEBI SMILES Value:   CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 ChEBI Substance ID:   135610140 ChEBI URL:   ChEBI:63631 ChemSpider ID:   4447672 Ontomatica Chemical Accession Key (OnChAKey):   KJADKKWYZYXHBB_XBWDGYHZSA_N_000_000000 PubChem Compound ID:   5284627