Item 1 of 4 (back to results) next imetit dihydrobromide A hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > histaminergic drug [CHEBI:37957] > histamine agonist [CHEBI:35678] > H4-receptor agonist [CHEBI:64155] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   histaminergic drug [CHEBI:37957] (94)   histamine agonist [CHEBI:35678] (10)   H3-receptor agonist [CHEBI:64154] (3)   imetit dihydrobromide [CHEBI:64151] (1)  H4-receptor agonist [CHEBI:64155] (4)   imetit dihydrobromide [CHEBI:64151] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   bromine molecular entity [CHEBI:22928] (199)   bromide salt [CHEBI:22925] (45)   organic bromide salt [CHEBI:48369] (33)   hydrobromide [CHEBI:48367] (13)   imetit dihydrobromide [CHEBI:64151] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   bromide salt [CHEBI:22925] (45)   organic bromide salt [CHEBI:48369] (33)   hydrobromide [CHEBI:48367] (13)   imetit dihydrobromide [CHEBI:64151] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic halide salt [CHEBI:51069] (386)   organic bromide salt [CHEBI:48369] (33)   hydrobromide [CHEBI:48367] (13)   imetit dihydrobromide [CHEBI:64151] (1)  halide salt [CHEBI:33958] (423)   bromide salt [CHEBI:22925] (45)   organic bromide salt [CHEBI:48369] (33)   hydrobromide [CHEBI:48367] (13)   imetit dihydrobromide [CHEBI:64151] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   bromide salt [CHEBI:22925] (45)   organic bromide salt [CHEBI:48369] (33)   hydrobromide [CHEBI:48367] (13)   imetit dihydrobromide [CHEBI:64151] (1) ChEBI Compound Accession Identifier:   [CHEBI:64151] ChEBI Compound Description:   A hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration. ChEBI Compound Identification Number:   64151 ChEBI InChI Value:   "InChI=1S/C6H10N4S.2BrH/c7-6(8)11-2-1-5-3-9-4-10-5;;/h3-4H,1-2H2,(H3,7,8)(H,9,10);2*1H" ChEBI InChIKey Value:   DOBOYMKCRRLTRF-UHFFFAOYSA-N ChEBI Compound Name:   imetit dihydrobromide ChEBI SMILES Value:   Br.Br.NC(=N)SCCc1c[nH]cn1 ChEBI Substance ID:   135610594 ChEBI URL:   ChEBI:64151 ChemSpider ID:   10131821 Ontomatica Chemical Accession Key (OnChAKey):   DOBOYMKCRRLTRF_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   11957573