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pizotifen malate
A malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache attacks during cluster periods.


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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 neurotransmitter agent [CHEBI:35942] (471) 
 histaminergic drug [CHEBI:37957] (94) 
 histamine antagonist [CHEBI:37956] (87) 
 pizotifen malate [CHEBI:50213] (1)
 cholinergic drug [CHEBI:38323] (108) 
 cholinergic antagonist [CHEBI:48873] (84) 
 muscarinic antagonist [CHEBI:48876] (61) 
 pizotifen malate [CHEBI:50213] (1)
 serotonergic drug [CHEBI:48278] (109) 
 serotonergic antagonist [CHEBI:48279] (52) 
 pizotifen malate [CHEBI:50213] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 malate salt [CHEBI:50220] (3) 
 pizotifen malate [CHEBI:50213] (1)
ChEBI Compound Accession Identifier  [CHEBI:50213]
ChEBI Compound Description  A malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache attacks during cluster periods.
ChEBI Compound Identification Number  50213
ChEBI InChI Value  "InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,1H2,(H,6,7)(H,8,9)"
ChEBI InChIKey Value  IWAWCPZVTXCFKD-UHFFFAOYSA-N
ChEBI Compound Name  pizotifen malate
ChEBI SMILES Value  OC(CC(O)=O)C(O)=O.CN1CCC(CC1)=C1c2ccccc2CCc2sccc12
ChEBI Substance ID  135668218
ChEBI URL  ChEBI:50213
ChemSpider ID  147809
Ontomatica Chemical Accession Key (OnChAKey)  IWAWCPZVTXCFKD_UHFFFAOYSA_N_000_000000
PubChem Compound ID  168993