Item 1 of 1 (back to results) (S)-fenfluramine The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > serotonergic drug [CHEBI:48278] > serotonergic agonist [CHEBI:35941] > (S)-fenfluramine [CHEBI:439329] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   serotonergic drug [CHEBI:48278] (109)   serotonergic agonist [CHEBI:35941] (41)   (S)-fenfluramine [CHEBI:439329] (1)  serotonin uptake inhibitor [CHEBI:50949] (21)   (S)-fenfluramine [CHEBI:439329] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   appetite regulator [CHEBI:50780] (13)   appetite depressant [CHEBI:50507] (12)   (S)-fenfluramine [CHEBI:439329] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   fenfluramine [CHEBI:5000] (3)   (S)-fenfluramine [CHEBI:439329] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   fenfluramine [CHEBI:5000] (3)   (S)-fenfluramine [CHEBI:439329] (1)  organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   fenfluramine [CHEBI:5000] (3)   (S)-fenfluramine [CHEBI:439329] (1) ChEBI Compound Accession Identifier:   [CHEBI:439329] ChEBI Compound Description:   The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects. ChEBI Compound Identification Number:   439329 ChEBI InChI Value:   InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1 ChEBI InChIKey Value:   DBGIVFWFUFKIQN-VIFPVBQESA-N ChEBI Compound Name:   (S)-fenfluramine ChEBI SMILES Value:   CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F ChEBI Substance ID:   85629918 ChEBI URL:   ChEBI:439329 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   DBGIVFWFUFKIQN_VIFPVBQESA_N_000_000000 PubChem Compound ID:   66265