Item 1 of 1 (back to results) domperidone maleate The maleic acid salt of domperidone. A dopamine antagonist, domperidone is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The maleate salt is used in tablet preparations, while the free base is used in oral suspensions.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > dopaminergic agent [CHEBI:48560] > dopaminergic antagonist [CHEBI:48561] > domperidone maleate [CHEBI:59812] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   dopaminergic agent [CHEBI:48560] (99)   dopaminergic antagonist [CHEBI:48561] (48)   domperidone maleate [CHEBI:59812] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antiemetic [CHEBI:50919] (41)   domperidone maleate [CHEBI:59812] (1) 08. Chemical Category  08. Chemical Category  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   maleate salt [CHEBI:50221] (31)   domperidone maleate [CHEBI:59812] (1) ChEBI Compound Accession Identifier:   [CHEBI:59812] ChEBI Compound Description:   The maleic acid salt of domperidone. A dopamine antagonist, domperidone is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The maleate salt is used in tablet preparations, while the free base is used in oral suspensions. ChEBI Compound Identification Number:   59812 ChEBI InChI Value:   "InChI=1S/C22H24ClN5O2.C4H4O4/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29;5-3(6)1-2-4(7)8/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30);1-2H,(H,5,6)(H,7,8)/b;2-1-" ChEBI InChIKey Value:   OAUUYDZHCOULIO-BTJKTKAUSA-N ChEBI Compound Name:   domperidone maleate ChEBI SMILES Value:   [O-]C(=O)\\C=C/C([O-])=O.Clc1ccc2N(C3CCN(CCCN4C(=O)[NH2+]c5ccccc45)CC3)C(=O)[NH2+]c2c1 ChEBI Substance ID:   99319729 ChEBI URL:   ChEBI:59812 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   OAUUYDZHCOULIO_BTJKTKAUSA_N_000_000000 PubChem Compound ID:   46878575