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pergolide mesylate
A methanesulfonate salt obtained from pergolide by mixing eqimolar amount of pergolide and methanesulfonic acid. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.


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03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > dopaminergic agent [CHEBI:48560] > dopamine agonist [CHEBI:51065] > pergolide mesylate [CHEBI:8021]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 neurotransmitter agent [CHEBI:35942] (471) 
 dopaminergic agent [CHEBI:48560] (99) 
 dopamine agonist [CHEBI:51065] (26) 
 pergolide mesylate [CHEBI:8021] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antidyskinesia agent [CHEBI:66956] (43) 
 antiparkinson drug [CHEBI:48407] (41) 
 pergolide mesylate [CHEBI:8021] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 sulfur molecular entity [CHEBI:26835] (1541) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 pergolide mesylate [CHEBI:8021] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 pergolide mesylate [CHEBI:8021] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 pergolide mesylate [CHEBI:8021] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organosulfonate salt [CHEBI:64382] (37) 
 methanesulfonate salt [CHEBI:38037] (28) 
 pergolide mesylate [CHEBI:8021] (1)
ChEBI Compound Accession Identifier  [CHEBI:8021]
ChEBI Compound Description  A methanesulfonate salt obtained from pergolide by mixing eqimolar amount of pergolide and methanesulfonic acid. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.
ChEBI Compound Identification Number  8021
ChEBI InChI Value  "InChI=1S/C19H26N2S.CH4O3S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21;1-5(2,3)4/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3;1H3,(H,2,3,4)/t13-,16-,18-;/m1./s1"
ChEBI InChIKey Value  UWCVGPLTGZWHGS-ZORIOUSZSA-N
ChEBI Compound Name  pergolide mesylate
ChEBI SMILES Value  CS(O)(=O)=O.[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@@H](CSC)CN2CCC
ChEBI Substance ID  135610172
ChEBI URL  ChEBI:8021
ChemSpider ID  43504
Ontomatica Chemical Accession Key (OnChAKey)  UWCVGPLTGZWHGS_ZORIOUSZSA_N_000_000000
PubChem Compound ID  47812