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benserazide hydrochloride
A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.


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03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > dopaminergic agent [CHEBI:48560] > benserazide hydrochloride [CHEBI:31262]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 aromatic-L-amino-acid decarboxylase inhibitor [CHEBI:59321] (4) 
 benserazide hydrochloride [CHEBI:31262] (1)
 pharmacological uses [CHEBI:52210] (736) 
 neurotransmitter agent [CHEBI:35942] (471) 
 dopaminergic agent [CHEBI:48560] (99) 
 benserazide hydrochloride [CHEBI:31262] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antidyskinesia agent [CHEBI:66956] (43) 
 antiparkinson drug [CHEBI:48407] (41) 
 benserazide hydrochloride [CHEBI:31262] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 halogen molecular entity [CHEBI:24471] (1475) 
 chlorine molecular entity [CHEBI:23117] (884) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 benserazide hydrochloride [CHEBI:31262] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 benserazide hydrochloride [CHEBI:31262] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organic halide salt [CHEBI:51069] (386) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 benserazide hydrochloride [CHEBI:31262] (1)
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 benserazide hydrochloride [CHEBI:31262] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 benserazide hydrochloride [CHEBI:31262] (1)
ChEBI Compound Accession Identifier  [CHEBI:31262]
ChEBI Compound Description  A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.
ChEBI Compound Identification Number  31262
ChEBI InChI Value  "InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H"
ChEBI InChIKey Value  ULFCBIUXQQYDEI-UHFFFAOYSA-N
ChEBI Compound Name  benserazide hydrochloride
ChEBI SMILES Value  Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
ChEBI Substance ID  135610206
ChEBI URL  ChEBI:31262
ChemSpider ID  25109
Ontomatica Chemical Accession Key (OnChAKey)  ULFCBIUXQQYDEI_UHFFFAOYSA_N_000_000000
PubChem Compound ID  26964