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E-3810
A hydrochloride salt obtained by reaction of 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide with one equivalent of hydrochloric acid. E-3810 is a dual VEGFR and FGFR inhibitor


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03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > antagonist [CHEBI:48706] > vascular endothelial growth factor receptor antagonist [CHEBI:65207]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 antagonist [CHEBI:48706] (126) 
 fibroblast growth factor receptor antagonist [CHEBI:63457] (8) 
 E-3810 [CHEBI:65138] (1)
 vascular endothelial growth factor receptor antagonist [CHEBI:65207] (5) 
 E-3810 [CHEBI:65138] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antineoplastic agent [CHEBI:35610] (760) 
 E-3810 [CHEBI:65138] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 halogen molecular entity [CHEBI:24471] (1475) 
 chlorine molecular entity [CHEBI:23117] (884) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 E-3810 [CHEBI:65138] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 E-3810 [CHEBI:65138] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organic halide salt [CHEBI:51069] (386) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 E-3810 [CHEBI:65138] (1)
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 E-3810 [CHEBI:65138] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 E-3810 [CHEBI:65138] (1)
ChEBI Compound Accession Identifier  [CHEBI:65138]
ChEBI Compound Description  A hydrochloride salt obtained by reaction of 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide with one equivalent of hydrochloric acid. E-3810 is a dual VEGFR and FGFR inhibitor
ChEBI Compound Identification Number  65138
ChEBI InChI Value  "InChI=1S/C26H25N3O4.ClH/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26;/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30);1H"
ChEBI InChIKey Value  QHPVWTJTATVJBR-UHFFFAOYSA-N
ChEBI Compound Name  E-3810
ChEBI SMILES Value  Cl.CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12
ChEBI Substance ID  160644866
ChEBI URL  ChEBI:65138
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  QHPVWTJTATVJBR_UHFFFAOYSA_N_000_000000
PubChem Compound ID  57379018