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tenofovir (anhydrous)
A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.


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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antiviral agent [CHEBI:22587] > antiviral drug [CHEBI:36044] > tenofovir (anhydrous) [CHEBI:63625]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 antimicrobial agent [CHEBI:33281] (927) 
 antiviral agent [CHEBI:22587] (216) 
 antiviral drug [CHEBI:36044] (50) 
 tenofovir (anhydrous) [CHEBI:63625] (1)
 anti-HIV agent [CHEBI:64946] (126) 
 anti-HIV-1 agent [CHEBI:64947] (79) 
 HIV-1 reverse transcriptase inhibitor [CHEBI:53756] (30) 
 tenofovir (anhydrous) [CHEBI:63625] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 phosphorus molecular entity [CHEBI:26082] (2769) 
 phosphorus oxoacids and derivatives [CHEBI:36360] (2691) 
 phosphonic acids [CHEBI:26069] (25) 
 tenofovir (anhydrous) [CHEBI:63625] (1)
ChEBI Compound Accession Identifier  [CHEBI:63625]
ChEBI Compound Description  A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
ChEBI Compound Identification Number  63625
ChEBI InChI Value  InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
ChEBI InChIKey Value  SGOIRFVFHAKUTI-ZCFIWIBFSA-N
ChEBI Compound Name  tenofovir (anhydrous)
ChEBI SMILES Value  C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(O)=O
ChEBI Substance ID  135611180
ChEBI URL  ChEBI:63625
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  SGOIRFVFHAKUTI_ZCFIWIBFSA_N_000_000000
PubChem Compound ID  464205