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trisodium phosphonoformate
The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.


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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antiviral agent [CHEBI:22587] > antiviral drug [CHEBI:36044] > trisodium phosphonoformate [CHEBI:141644]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 antimicrobial agent [CHEBI:33281] (927) 
 antiviral agent [CHEBI:22587] (216) 
 antiviral drug [CHEBI:36044] (50) 
 trisodium phosphonoformate [CHEBI:141644] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 alkali metal molecular entity [CHEBI:33296] (279) 
 sodium molecular entity [CHEBI:26712] (216) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 trisodium phosphonoformate [CHEBI:141644] (1)
 alkali metal salt [CHEBI:35479] (248) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 trisodium phosphonoformate [CHEBI:141644] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 one-carbon compound [CHEBI:64708] (104) 
 trisodium phosphonoformate [CHEBI:141644] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organic sodium salt [CHEBI:38700] (187) 
 trisodium phosphonoformate [CHEBI:141644] (1)
 alkali metal salt [CHEBI:35479] (248) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 trisodium phosphonoformate [CHEBI:141644] (1)
ChEBI Compound Accession Identifier  [CHEBI:141644]
ChEBI Compound Description  The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
ChEBI Compound Identification Number  141644
ChEBI InChI Value  "InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3"
ChEBI InChIKey Value  DFHAXXVZCFXGOQ-UHFFFAOYSA-K
ChEBI Compound Name  trisodium phosphonoformate
ChEBI SMILES Value  [Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O
ChEBI Substance ID  85341314
ChEBI URL  ChEBI:141644
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  DFHAXXVZCFXGOQ_UHFFFAOYSA_K_000_000000
PubChem Compound ID  44561