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myriocin
"An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity."

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03. Biological Effects of Specific Chemicals

			biochemical uses [CHEBI:52206] (3306)

					enzyme inhibitor [CHEBI:23924] (825)

							serine palmitoyltransferase inhibitor [CHEBI:59647] (2)

myriocin [CHEBI:582124] (1)

					metabolite [CHEBI:25212] (2692)

						secondary metabolite [CHEBI:26619] (2225)

myriocin [CHEBI:582124] (1)

			antimicrobial agent [CHEBI:33281] (927)

					antibiotic [CHEBI:22582] (193)

myriocin [CHEBI:582124] (1)

					antifungal agent [CHEBI:35718] (130)

myriocin [CHEBI:582124] (1)

			immunomodulator [CHEBI:50846] (61)

				immunosuppressive agent [CHEBI:35705] (43)

myriocin [CHEBI:582124] (1)

08. Chemical Category

			main group molecular entity [CHEBI:33579] (25650)

					s-block molecular entity [CHEBI:33674] (7287)

							hydrogen molecular entity [CHEBI:33608] (6932)

								hydroxides [CHEBI:24651] (5641)

									oxoacid [CHEBI:24833] (3119)

carbon oxoacid [CHEBI:35605] (3012)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

					p-block molecular entity [CHEBI:33675] (25343)

						pnictogen molecular entity [CHEBI:33302] (10027)

								nitrogen molecular entity [CHEBI:51143] (7930)

									organonitrogen compound [CHEBI:35352] (6705)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

organic amino compound [CHEBI:50047] (2472)

amine [CHEBI:32952] (179)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

						chalcogen molecular entity [CHEBI:33304] (15225)

								oxygen molecular entity [CHEBI:25806] (14414)

hydroxides [CHEBI:24651] (5641)

oxoacid [CHEBI:24833] (3119)

carbon oxoacid [CHEBI:35605] (3012)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

organooxygen compound [CHEBI:36963] (11352)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

carbon oxoacid [CHEBI:35605] (3012)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

carbonyl compound [CHEBI:36586] (5928)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

								organochalcogen compound [CHEBI:36962] (11874)

									organooxygen compound [CHEBI:36963] (11352)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

carbon oxoacid [CHEBI:35605] (3012)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

carbonyl compound [CHEBI:36586] (5928)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

						carbon group molecular entity [CHEBI:33582] (23847)

							organic molecular entity [CHEBI:50860] (23769)

								lipid [CHEBI:18059] (3532)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

								heteroorganic entity [CHEBI:33285] (15197)

organonitrogen compound [CHEBI:35352] (6705)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

organic amino compound [CHEBI:50047] (2472)

amine [CHEBI:32952] (179)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

organochalcogen compound [CHEBI:36962] (11874)

organooxygen compound [CHEBI:36963] (11352)

sphingolipid [CHEBI:26739] (439)

sphingoid [CHEBI:35785] (92)

myriocin [CHEBI:582124] (1)

carbon oxoacid [CHEBI:35605] (3012)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

carbonyl compound [CHEBI:36586] (5928)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

								organic amino compound [CHEBI:50047] (2472)

amine [CHEBI:32952] (179)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

								organic acid [CHEBI:64709] (3008)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

								organic molecule [CHEBI:72695] (11399)

									organic oxo compound [CHEBI:36587] (5932)

carbonyl compound [CHEBI:36586] (5928)

carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

			polyatomic entity [CHEBI:36357] (18777)

				molecule [CHEBI:25367] (11520)

						organic molecule [CHEBI:72695] (11399)

							organic oxo compound [CHEBI:36587] (5932)

								carbonyl compound [CHEBI:36586] (5928)

									carboxylic acid [CHEBI:33575] (3005)

monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

				heteroatomic molecular entity [CHEBI:37577] (13672)

					hydroxides [CHEBI:24651] (5641)

						oxoacid [CHEBI:24833] (3119)

							carbon oxoacid [CHEBI:35605] (3012)

								carboxylic acid [CHEBI:33575] (3005)

									monocarboxylic acid [CHEBI:25384] (1620)

fatty acid [CHEBI:35366] (487)

nitrogen-containing fatty acid [CHEBI:60690] (6)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

									amino acid [CHEBI:33709] (959)

alpha-amino acid [CHEBI:10208] (233)

myriocin [CHEBI:582124] (1)

amino fatty acid [CHEBI:59650] (6)

alpha-amino fatty acid [CHEBI:59755] (2)

myriocin [CHEBI:582124] (1)

ChEBI Compound Accession Identifier:

[CHEBI:582124]

ChEBI Compound Description:

"An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity."

ChEBI Compound Identification Number:

582124

ChEBI InChI Value:

InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1

ChEBI InChIKey Value:

ZZIKIHCNFWXKDY-GNTQXERDSA-N

ChEBI Compound Name:

myriocin

ChEBI SMILES Value:

CCCCCCC(=O)CCCCCC\C=C\C[C@@H](O)[C@H](O)[C@@](N)(CO)C(O)=O

ChEBI Substance ID:

87283396

ChEBI URL:

ChEBI:582124

ChemSpider ID:

4942874

Ontomatica Chemical Accession Key (OnChAKey):

ZZIKIHCNFWXKDY_GNTQXERDSA_N_000_000000

PubChem Compound ID:

6438394