Item 1 of 1 (back to results) pemetrexed disodium heptahydrate An organic sodium salt that is the heptahydrate form of pemetrexed disodium. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > dihydrofolate reductase inhibitor [CHEBI:50683] > pemetrexed disodium heptahydrate [CHEBI:63723] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   dihydrofolate reductase inhibitor [CHEBI:50683] (7)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  thymidylate synthase inhibitor [CHEBI:63720] (3)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  glycinamide ribonucleotide formyltransferase inhibitor [CHEBI:63721] (3)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  antimetabolite [CHEBI:35221] (34)   pemetrexed disodium heptahydrate [CHEBI:63723] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   pemetrexed disodium heptahydrate [CHEBI:63723] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   alkali metal molecular entity [CHEBI:33296] (279)   sodium molecular entity [CHEBI:26712] (216)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   pemetrexed disodium heptahydrate [CHEBI:63723] (1)  addition compound [CHEBI:35504] (113)   hydrate [CHEBI:35505] (111)   pemetrexed disodium heptahydrate [CHEBI:63723] (1) ChEBI Compound Accession Identifier:   [CHEBI:63723] ChEBI Compound Description:   An organic sodium salt that is the heptahydrate form of pemetrexed disodium. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). ChEBI Compound Identification Number:   63723 ChEBI InChI Value:   "InChI=1S/C20H21N5O6.2Na.7H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;;;;;;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;;7*1H2/q;2*+1;;;;;;;/p-2/t13-;;;;;;;;;/m0........./s1" ChEBI InChIKey Value:   QJVSMHJWAOSBMD-MYXYZBIASA-L ChEBI Compound Name:   pemetrexed disodium heptahydrate ChEBI SMILES Value:   O.O.O.O.O.O.O.[Na+].[Na+].Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1 ChEBI Substance ID:   135610835 ChEBI URL:   ChEBI:63723 ChemSpider ID:   23089153 Ontomatica Chemical Accession Key (OnChAKey):   QJVSMHJWAOSBMD_MYXYZBIASA_L_000_000000 PubChem Compound ID:   23725084