Item 2 of 4 (back to results) previous next sodium 8-bromo-3',5'-cyclic GMP An organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > agonist [CHEBI:48705] > protein kinase agonist [CHEBI:64106] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   agonist [CHEBI:48705] (68)   protein kinase agonist [CHEBI:64106] (4)   protein kinase G agonist [CHEBI:64105] (2)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   neuromuscular agent [CHEBI:51372] (51)   muscle relaxant [CHEBI:51371] (47)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   alkali metal molecular entity [CHEBI:33296] (279)   sodium molecular entity [CHEBI:26712] (216)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic sodium salt [CHEBI:38700] (187)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1)  alkali metal salt [CHEBI:35479] (248)   sodium salt [CHEBI:26714] (213)   organic sodium salt [CHEBI:38700] (187)   sodium 8-bromo-3',5'-cyclic GMP [CHEBI:64104] (1) ChEBI Compound Accession Identifier:   [CHEBI:64104] ChEBI Compound Description:   An organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. ChEBI Compound Identification Number:   64104 ChEBI InChI Value:   "InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1" ChEBI InChIKey Value:   ZJRFCXHKYQVNFK-YEOHUATISA-M ChEBI Compound Name:   sodium 8-bromo-3',5'-cyclic GMP ChEBI SMILES Value:   [Na+].Nc1nc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc2c(=O)[nH]1 ChEBI Substance ID:   135610561 ChEBI URL:   ChEBI:64104 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   ZJRFCXHKYQVNFK_YEOHUATISA_M_000_000000 PubChem Compound ID:   23702959