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perampanel hydrate
A hydrate obtained by combining four molecules of perampanel with three molecules of water. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.


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03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > antagonist [CHEBI:48706] > AMPA receptor antagonist [CHEBI:71014]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 antagonist [CHEBI:48706] (126) 
 AMPA receptor antagonist [CHEBI:71014] (2) 
 perampanel hydrate [CHEBI:71015] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 central nervous system drug [CHEBI:35470] (217) 
 central nervous system depressant [CHEBI:35488] (90) 
 anticonvulsant [CHEBI:35623] (39) 
 perampanel hydrate [CHEBI:71015] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 addition compound [CHEBI:35504] (113) 
 hydrate [CHEBI:35505] (111) 
 perampanel hydrate [CHEBI:71015] (1)
ChEBI Compound Accession Identifier  [CHEBI:71015]
ChEBI Compound Description  A hydrate obtained by combining four molecules of perampanel with three molecules of water. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.
ChEBI Compound Identification Number  71015
ChEBI InChI Value  "InChI=1S/4C23H15N3O.3H2O/c4*24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19;;;/h4*1-14,16H;3*1H2"
ChEBI InChIKey Value  PDWMJDKMSASBNE-UHFFFAOYSA-N
ChEBI Compound Name  perampanel hydrate
ChEBI SMILES Value  O.O.O.O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N.O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N.O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N.O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
ChEBI Substance ID  160646232
ChEBI URL  ChEBI:71015
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  PDWMJDKMSASBNE_UHFFFAOYSA_N_000_000000
PubChem Compound ID  70679123