Item 2 of 126 (back to results) previous next delavirdine mesylate The monomethanesulfonic acid salt of delavirdine, a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.

Current search: 03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antiviral agent [CHEBI:22587] > anti-HIV agent [CHEBI:64946] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  antimicrobial agent [CHEBI:33281] (927)   antiviral agent [CHEBI:22587] (216)   antiviral drug [CHEBI:36044] (50)   delavirdine mesylate [CHEBI:4379] (1)  anti-HIV agent [CHEBI:64946] (126)   anti-HIV-1 agent [CHEBI:64947] (79)   HIV-1 reverse transcriptase inhibitor [CHEBI:53756] (30)   delavirdine mesylate [CHEBI:4379] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   sulfur molecular entity [CHEBI:26835] (1541)   organosulfur compound [CHEBI:33261] (1005)   methanesulfonates [CHEBI:48544] (33)   methanesulfonate salt [CHEBI:38037] (28)   delavirdine mesylate [CHEBI:4379] (1)  organochalcogen compound [CHEBI:36962] (11874)   organosulfur compound [CHEBI:33261] (1005)   methanesulfonates [CHEBI:48544] (33)   methanesulfonate salt [CHEBI:38037] (28)   delavirdine mesylate [CHEBI:4379] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organochalcogen compound [CHEBI:36962] (11874)   organosulfur compound [CHEBI:33261] (1005)   methanesulfonates [CHEBI:48544] (33)   methanesulfonate salt [CHEBI:38037] (28)   delavirdine mesylate [CHEBI:4379] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organosulfonate salt [CHEBI:64382] (37)   methanesulfonate salt [CHEBI:38037] (28)   delavirdine mesylate [CHEBI:4379] (1) ChEBI Compound Accession Identifier:   [CHEBI:4379] ChEBI Compound Description:   The monomethanesulfonic acid salt of delavirdine, a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection. ChEBI Compound Identification Number:   4379 ChEBI InChI Value:   "InChI=1S/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20;1-5(2,3)4/h4-8,13-15,24-26H,9-12H2,1-3H3;1H3,(H,2,3,4)" ChEBI InChIKey Value:   MEPNHSOMXMALDZ-UHFFFAOYSA-N ChEBI Compound Name:   delavirdine mesylate ChEBI SMILES Value:   CS(O)(=O)=O.CC(C)Nc1cccnc1N1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1 ChEBI Substance ID:   99313628 ChEBI URL:   ChEBI:4379 ChemSpider ID:   390125 Ontomatica Chemical Accession Key (OnChAKey):   MEPNHSOMXMALDZ_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   441386