Item 14 of 37 (back to results) previous next sulindac sulfone A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > cyclooxygenase inhibitor [CHEBI:35544] > cyclooxygenase 2 inhibitor [CHEBI:50629] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   apoptosis inducer [CHEBI:68495] (23)   sulindac sulfone [CHEBI:64212] (1)  enzyme inhibitor [CHEBI:23924] (825)   lipoxygenase inhibitor [CHEBI:35856] (23)   arachidonate 5-lipoxygenase inhibitor [CHEBI:64964] (9)   sulindac sulfone [CHEBI:64212] (1)  cyclooxygenase inhibitor [CHEBI:35544] (58)   cyclooxygenase 2 inhibitor [CHEBI:50629] (37)   sulindac sulfone [CHEBI:64212] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   sulfur molecular entity [CHEBI:26835] (1541)   organosulfur compound [CHEBI:33261] (1005)   sulfone [CHEBI:35850] (29)   sulindac sulfone [CHEBI:64212] (1)  organochalcogen compound [CHEBI:36962] (11874)   organosulfur compound [CHEBI:33261] (1005)   sulfone [CHEBI:35850] (29)   sulindac sulfone [CHEBI:64212] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organochalcogen compound [CHEBI:36962] (11874)   organosulfur compound [CHEBI:33261] (1005)   sulfone [CHEBI:35850] (29)   sulindac sulfone [CHEBI:64212] (1) ChEBI Compound Accession Identifier:   [CHEBI:64212] ChEBI Compound Description:   A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor. ChEBI Compound Identification Number:   64212 ChEBI InChI Value:   InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- ChEBI InChIKey Value:   MVGSNCBCUWPVDA-MFOYZWKCSA-N ChEBI Compound Name:   sulindac sulfone ChEBI SMILES Value:   CC1=C(CC(O)=O)c2cc(F)ccc2C\\1=C/c1ccc(cc1)S(C)(=O)=O ChEBI Substance ID:   135610803 ChEBI URL:   ChEBI:64212 ChemSpider ID:   4582441 Ontomatica Chemical Accession Key (OnChAKey):   MVGSNCBCUWPVDA_MFOYZWKCSA_N_000_000000 PubChem Compound ID:   5472495