Item 18 of 18 (back to results) previous bedaquiline fumarate A fumarate salt prepared from equimolar amounts of bedaquiline and fumaric acid. It is used in combination therapy for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > electron-transport chain inhibitor [CHEBI:38496] > respiratory-chain inhibitor [CHEBI:38497] > mitochondrial respiratory-chain inhibitor [CHEBI:25355] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   electron-transport chain inhibitor [CHEBI:38496] (27)   respiratory-chain inhibitor [CHEBI:38497] (23)   mitochondrial respiratory-chain inhibitor [CHEBI:25355] (18)   ATP synthase inhibitor [CHEBI:20854] (3)   bedaquiline fumarate [CHEBI:72295] (1)  antimicrobial agent [CHEBI:33281] (927)   antibacterial agent [CHEBI:33282] (317)   antibacterial drug [CHEBI:36047] (177)   antimycobacterial drug [CHEBI:64912] (46)   antitubercular agent [CHEBI:33231] (29)   bedaquiline fumarate [CHEBI:72295] (1) 08. Chemical Category  08. Chemical Category  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   fumarate salt [CHEBI:50921] (9)   bedaquiline fumarate [CHEBI:72295] (1) ChEBI Compound Accession Identifier:   [CHEBI:72295] ChEBI Compound Description:   A fumarate salt prepared from equimolar amounts of bedaquiline and fumaric acid. It is used in combination therapy for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. ChEBI Compound Identification Number:   72295 ChEBI InChI Value:   "InChI=1S/C32H31BrN2O2.C4H4O4/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3;5-3(6)1-2-4(7)8/h4-17,20-21,30,36H,18-19H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t30-,32-;/m1./s1" ChEBI InChIKey Value:   ZLVSPMRFRHMMOY-WWCCMVHESA-N ChEBI Compound Name:   bedaquiline fumarate ChEBI SMILES Value:   OC(=O)\C=C\C(O)=O.COc1nc2ccc(Br)cc2cc1[C@@H](c1ccccc1)[C@@](O)(CCN(C)C)c1cccc2ccccc12 ChEBI Substance ID:   160962912 ChEBI URL:   ChEBI:72295 ChemSpider ID:   28528191 Ontomatica Chemical Accession Key (OnChAKey):   ZLVSPMRFRHMMOY_WWCCMVHESA_N_000_000000 PubChem Compound ID:   24812732