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N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
The dipeptide obtained by coupling N-benzyloxycarbonyl-L-tyrosine with the hydroxamic acid derivative of L-leucine. It is an inhibitor of the metallo-protease enzyme, pseudolysin (EC 3.4.24.36).


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > protease inhibitor [CHEBI:37670] > metalloendopeptidase inhibitor [CHEBI:59107]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 protease inhibitor [CHEBI:37670] (37) 
 metalloendopeptidase inhibitor [CHEBI:59107] (3) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 amide [CHEBI:32988] (1863) 
 primary amide [CHEBI:33256] (1586) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 oligopeptide [CHEBI:7755] (479) 
 dipeptide [CHEBI:46761] (253) 
 N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide [CHEBI:10099] (1)
ChEBI Compound Accession Identifier  [CHEBI:10099]
ChEBI Compound Description  The dipeptide obtained by coupling N-benzyloxycarbonyl-L-tyrosine with the hydroxamic acid derivative of L-leucine. It is an inhibitor of the metallo-protease enzyme, pseudolysin (EC 3.4.24.36).
ChEBI Compound Identification Number  10099
ChEBI InChI Value  InChI=1S/C23H29N3O6/c1-15(2)12-19(22(29)26-31)24-21(28)20(13-16-8-10-18(27)11-9-16)25-23(30)32-14-17-6-4-3-5-7-17/h3-11,15,19-20,27,31H,12-14H2,1-2H3,(H,24,28)(H,25,30)(H,26,29)/t19-,20-/m0/s1
ChEBI InChIKey Value  YBHTVSIBHATTHP-PMACEKPBSA-N
ChEBI Compound Name  N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
ChEBI SMILES Value  CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NO
ChEBI Substance ID  92740962
ChEBI URL  ChEBI:10099
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  YBHTVSIBHATTHP_PMACEKPBSA_N_000_000000
PubChem Compound ID  45266500