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8-bromo-3',5'-cyclic GMP
A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.

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03. Biological Effects of Specific Chemicals

			pharmacological uses [CHEBI:52210] (736)

				agonist [CHEBI:48705] (68)

					protein kinase agonist [CHEBI:64106] (4)

						protein kinase G agonist [CHEBI:64105] (2)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

05. Industrial Uses

			pharmaceutical [CHEBI:52217] (1978)

				drug [CHEBI:23888] (1930)

					neuromuscular agent [CHEBI:51372] (51)

						muscle relaxant [CHEBI:51371] (47)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

08. Chemical Category

			main group molecular entity [CHEBI:33579] (25650)

					p-block molecular entity [CHEBI:33675] (25343)

						halogen molecular entity [CHEBI:24471] (1475)

								bromine molecular entity [CHEBI:22928] (199)

organobromine compound [CHEBI:37141] (138)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								halide [CHEBI:37578] (1402)

									organohalogen compound [CHEBI:36684] (976)

organobromine compound [CHEBI:37141] (138)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

						pnictogen molecular entity [CHEBI:33302] (10027)

								phosphorus molecular entity [CHEBI:26082] (2769)

organophosphorus compound [CHEBI:25710] (1528)

organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

phosphorus oxoacids and derivatives [CHEBI:36360] (2691)

phosphorus oxoacid derivative [CHEBI:36359] (2628)

phosphoric acid derivative [CHEBI:26079] (2611)

organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

phosphate [CHEBI:26020] (1522)

organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

phosphoric ester [CHEBI:37734] (1466)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								nitrogen molecular entity [CHEBI:51143] (7930)

									organonitrogen compound [CHEBI:35352] (6705)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

									nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

						carbon group molecular entity [CHEBI:33582] (23847)

							organic molecular entity [CHEBI:50860] (23769)

								heteroorganic entity [CHEBI:33285] (15197)

organic heterocyclic compound [CHEBI:24532] (5243)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organophosphorus compound [CHEBI:25710] (1528)

organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen compound [CHEBI:35352] (6705)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organohalogen compound [CHEBI:36684] (976)

organobromine compound [CHEBI:37141] (138)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								ester [CHEBI:35701] (3370)

phosphoric ester [CHEBI:37734] (1466)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								organic molecule [CHEBI:72695] (11399)

									organic cyclic compound [CHEBI:33832] (7633)

organic heterocyclic compound [CHEBI:24532] (5243)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic aromatic compound [CHEBI:33659] (3593)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

			polyatomic entity [CHEBI:36357] (18777)

				molecule [CHEBI:25367] (11520)

						cyclic compound [CHEBI:33595] (7817)

								polycyclic compound [CHEBI:33635] (4078)

heteropolycyclic compound [CHEBI:33671] (2613)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								bicyclic compound [CHEBI:33636] (1511)

heterobicyclic compound [CHEBI:33672] (1315)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								aromatic compound [CHEBI:33655] (3799)

organic aromatic compound [CHEBI:33659] (3593)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								organic cyclic compound [CHEBI:33832] (7633)

organic heterocyclic compound [CHEBI:24532] (5243)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic aromatic compound [CHEBI:33659] (3593)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								heterocyclic compound [CHEBI:5686] (5275)

									organic heterocyclic compound [CHEBI:24532] (5243)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

									heteropolycyclic compound [CHEBI:33671] (2613)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

									heterobicyclic compound [CHEBI:33672] (1315)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

						organic molecule [CHEBI:72695] (11399)

							organic cyclic compound [CHEBI:33832] (7633)

								organic heterocyclic compound [CHEBI:24532] (5243)

heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organonitrogen heterocyclic compound [CHEBI:38101] (3202)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

organic heteropolycyclic compound [CHEBI:38166] (2613)

organic heterobicyclic compound [CHEBI:27171] (1315)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

								organic aromatic compound [CHEBI:33659] (3593)

									heteroarene [CHEBI:33833] (1648)

imidazopyrimidine [CHEBI:35875] (321)

purines [CHEBI:26401] (320)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

nucleobase-containing molecular entity [CHEBI:61120] (573)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

				heteroatomic molecular entity [CHEBI:37577] (13672)

					oxoacid derivative [CHEBI:33241] (3254)

							phosphorus oxoacid derivative [CHEBI:36359] (2628)

								phosphoric acid derivative [CHEBI:26079] (2611)

									organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

									phosphate [CHEBI:26020] (1522)

organic phosphate [CHEBI:25703] (1511)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

									phosphoric ester [CHEBI:37734] (1466)

nucleoside phosphate [CHEBI:25608] (412)

nucleotide [CHEBI:36976] (398)

cyclic nucleotide [CHEBI:23447] (20)

nucleoside 3',5'-cyclic phosphate [CHEBI:18375] (10)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

purine nucleotide [CHEBI:26395] (129)

cyclic purine nucleotide [CHEBI:36982] (16)

3',5'-cyclic purine nucleotide [CHEBI:19834] (9)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

					halide [CHEBI:37578] (1402)

						organohalogen compound [CHEBI:36684] (976)

							organobromine compound [CHEBI:37141] (138)

8-bromo-3',5'-cyclic GMP [CHEBI:64108] (1)

ChEBI Compound Accession Identifier:

[CHEBI:64108]

ChEBI Compound Description:

A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.

ChEBI Compound Identification Number:

64108

ChEBI InChI Value:

InChI=1S/C10H11BrN5O7P/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18)/t2-,4-,5-,8-/m1/s1

ChEBI InChIKey Value:

YUFCOOWNNHGGOD-UMMCILCDSA-N

ChEBI Compound Name:

8-bromo-3',5'-cyclic GMP

ChEBI SMILES Value:

Nc1nc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Br)nc2c(=O)[nH]1

ChEBI Substance ID:

135610563

ChEBI URL:

ChEBI:64108

ChemSpider ID:

94575

Ontomatica Chemical Accession Key (OnChAKey):

YUFCOOWNNHGGOD_UMMCILCDSA_N_000_000000

PubChem Compound ID:

104767