Item 25 of 38 (back to results) previous next ruxolitinib phosphate A phosphate salt obtained by reaction ruxolitinib with one equivalent of phosphoric acid. Used for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > protein kinase inhibitor [CHEBI:37699] > tyrosine kinase inhibitor [CHEBI:38637] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   protein kinase inhibitor [CHEBI:37699] (69)   tyrosine kinase inhibitor [CHEBI:38637] (38)   Janus kinase inhibitor [CHEBI:66921] (4)   ruxolitinib phosphate [CHEBI:66917] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   ruxolitinib phosphate [CHEBI:66917] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   phosphorus molecular entity [CHEBI:26082] (2769)   phosphorus oxoacids and derivatives [CHEBI:36360] (2691)   phosphorus oxoacid derivative [CHEBI:36359] (2628)   phosphoric acid derivative [CHEBI:26079] (2611)   phosphate [CHEBI:26020] (1522)   phosphate salt [CHEBI:37853] (5)   ruxolitinib phosphate [CHEBI:66917] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   oxoacid derivative [CHEBI:33241] (3254)   phosphorus oxoacid derivative [CHEBI:36359] (2628)   phosphoric acid derivative [CHEBI:26079] (2611)   phosphate [CHEBI:26020] (1522)   phosphate salt [CHEBI:37853] (5)   ruxolitinib phosphate [CHEBI:66917] (1) ChEBI Compound Accession Identifier:   [CHEBI:66917] ChEBI Compound Description:   A phosphate salt obtained by reaction ruxolitinib with one equivalent of phosphoric acid. Used for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. ChEBI Compound Identification Number:   66917 ChEBI InChI Value:   "InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1" ChEBI InChIKey Value:   JFMWPOCYMYGEDM-XFULWGLBSA-N ChEBI Compound Name:   ruxolitinib phosphate ChEBI SMILES Value:   OP(O)(O)=O.N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 ChEBI Substance ID:   160645415 ChEBI URL:   ChEBI:66917 ChemSpider ID:   26286920 Ontomatica Chemical Accession Key (OnChAKey):   JFMWPOCYMYGEDM_XFULWGLBSA_N_000_000000 PubChem Compound ID:   25127112