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hernandonine
An isoquinoline alkaloid isolated from Hernandia ovigera and Lindera chunii and has been shown exhibit inhibitory activity against HIV-1 integrase .


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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antiviral agent [CHEBI:22587] > anti-HIV agent [CHEBI:64946] > anti-HIV-1 agent [CHEBI:64947] > HIV-1 integrase inhibitor [CHEBI:67268]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 hernandonine [CHEBI:66011] (1)
 antimicrobial agent [CHEBI:33281] (927) 
 antiviral agent [CHEBI:22587] (216) 
 anti-HIV agent [CHEBI:64946] (126) 
 anti-HIV-1 agent [CHEBI:64947] (79) 
 HIV-1 integrase inhibitor [CHEBI:67268] (16) 
 hernandonine [CHEBI:66011] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 alkaloid [CHEBI:22315] (473) 
 isoquinoline alkaloid [CHEBI:24921] (120) 
 hernandonine [CHEBI:66011] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 hernandonine [CHEBI:66011] (1)
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 hernandonine [CHEBI:66011] (1)
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 alkaloid [CHEBI:22315] (473) 
 isoquinoline alkaloid [CHEBI:24921] (120) 
 hernandonine [CHEBI:66011] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 hernandonine [CHEBI:66011] (1)
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 hernandonine [CHEBI:66011] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 polycyclic compound [CHEBI:33635] (4078) 
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 oxacycle [CHEBI:38104] (2002) 
 hernandonine [CHEBI:66011] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterohexacyclic compound [CHEBI:51914] (33) 
 hernandonine [CHEBI:66011] (1)
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 hernandonine [CHEBI:66011] (1)
ChEBI Compound Accession Identifier  [CHEBI:66011]
ChEBI Compound Description  An isoquinoline alkaloid isolated from Hernandia ovigera and Lindera chunii and has been shown exhibit inhibitory activity against HIV-1 integrase .
ChEBI Compound Identification Number  66011
ChEBI InChI Value  InChI=1S/C18H9NO5/c20-16-9-1-2-10-17(23-6-21-10)13(9)14-12-8(3-4-19-15(12)16)5-11-18(14)24-7-22-11/h1-5H,6-7H2
ChEBI InChIKey Value  QHFWZNALDDSHFJ-UHFFFAOYSA-N
ChEBI Compound Name  hernandonine
ChEBI SMILES Value  O=C1c2ccc3OCOc3c2-c2c3OCOc3cc3ccnc1c23
ChEBI Substance ID  160709956
ChEBI URL  ChEBI:66011
ChemSpider ID  437794
Ontomatica Chemical Accession Key (OnChAKey)  QHFWZNALDDSHFJ_UHFFFAOYSA_N_000_000000
PubChem Compound ID  500428