Item 7 of 24 (back to results) previous next nimodipine A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Current search: 03. Biological Effects of Specific Chemicals: biophysical uses [CHEBI:52208] > membrane transport modulator [CHEBI:38632] > calcium channel modulator [CHEBI:38808] > calcium channel blocker [CHEBI:38215] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biophysical uses [CHEBI:52208] (136)   membrane transport modulator [CHEBI:38632] (122)   calcium channel modulator [CHEBI:38808] (32)   calcium channel blocker [CHEBI:38215] (24)   nimodipine [CHEBI:7575] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antihypertensive agent [CHEBI:35674] (104)   nimodipine [CHEBI:7575] (1)  cardiovascular drug [CHEBI:35554] (162)   nimodipine [CHEBI:7575] (1)  vasodilator agent [CHEBI:35620] (65)   nimodipine [CHEBI:7575] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   monocyclic compound [CHEBI:33661] (2007)   heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   nimodipine [CHEBI:7575] (1) ChEBI Compound Accession Identifier:   [CHEBI:7575] ChEBI Compound Description:   A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. ChEBI Compound Identification Number:   7575 ChEBI InChI Value:   InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3 ChEBI InChIKey Value:   UIAGMCDKSXEBJQ-UHFFFAOYSA-N ChEBI Compound Name:   nimodipine ChEBI SMILES Value:   COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C ChEBI Substance ID:   135610175 ChEBI URL:   ChEBI:7575 ChemSpider ID:   4341 Ontomatica Chemical Accession Key (OnChAKey):   UIAGMCDKSXEBJQ_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   4497