Item 7 of 13 (back to results) previous next tibolone Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > agonist [CHEBI:48705] > hormone agonist [CHEBI:51060] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   agonist [CHEBI:48705] (68)   hormone agonist [CHEBI:51060] (13)   tibolone [CHEBI:32223] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   bone density conservation agent [CHEBI:50646] (18)   tibolone [CHEBI:32223] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   steroid [CHEBI:35341] (716)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  acetylenic compound [CHEBI:73474] (106)   terminal acetylenic compound [CHEBI:73477] (54)   tibolone [CHEBI:32223] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   polycyclic compound [CHEBI:33635] (4078)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1)  acetylenic compound [CHEBI:73474] (106)   terminal acetylenic compound [CHEBI:73477] (54)   tibolone [CHEBI:32223] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   hydroxy steroid [CHEBI:35350] (392)   17-hydroxy steroid [CHEBI:36838] (94)   17beta-hydroxy steroid [CHEBI:35343] (44)   tibolone [CHEBI:32223] (1) ChEBI Compound Accession Identifier:   [CHEBI:32223] ChEBI Compound Description:   Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. ChEBI Compound Identification Number:   32223 ChEBI InChI Value:   InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,17-19,23H,5-12H2,2-3H3/t13-,17-,18+,19-,20+,21+/m1/s1 ChEBI InChIKey Value:   WZDGZWOAQTVYBX-XOINTXKNSA-N ChEBI Compound Name:   tibolone ChEBI SMILES Value:   [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])[C@H](C)CC1=C2CCC(=O)C1 ChEBI Substance ID:   92741022 ChEBI URL:   ChEBI:32223 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   WZDGZWOAQTVYBX_XOINTXKNSA_N_000_000000 PubChem Compound ID:   444008