Item 9 of 57 (back to results) previous next clemastine 2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] > histaminergic drug [CHEBI:37957] > histamine antagonist [CHEBI:37956] > H1-receptor antagonist [CHEBI:37955] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   histaminergic drug [CHEBI:37957] (94)   histamine antagonist [CHEBI:37956] (87)   H1-receptor antagonist [CHEBI:37955] (57)   clemastine [CHEBI:3738] (1)  cholinergic drug [CHEBI:38323] (108)   cholinergic antagonist [CHEBI:48873] (84)   muscarinic antagonist [CHEBI:48876] (61)   clemastine [CHEBI:3738] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   dermatologic drug [CHEBI:50177] (49)   antipruritic drug [CHEBI:59683] (18)   clemastine [CHEBI:3738] (1)  anti-allergic agent [CHEBI:50857] (51)   clemastine [CHEBI:3738] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   monocyclic compound [CHEBI:33661] (2007)   heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyrrolidines [CHEBI:38260] (159)   N-alkylpyrrolidine [CHEBI:46775] (24)   clemastine [CHEBI:3738] (1) ChEBI Compound Accession Identifier:   [CHEBI:3738] ChEBI Compound Description:   2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions. ChEBI Compound Identification Number:   3738 ChEBI InChI Value:   InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1 ChEBI InChIKey Value:   YNNUSGIPVFPVBX-NHCUHLMSSA-N ChEBI Compound Name:   clemastine ChEBI SMILES Value:   [H][C@@]1(CCCN1C)CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1 ChEBI Substance ID:   96079549 ChEBI URL:   ChEBI:3738 ChemSpider ID:   25129 Ontomatica Chemical Accession Key (OnChAKey):   YNNUSGIPVFPVBX_NHCUHLMSSA_N_000_000000 PubChem Compound ID:   26987