Item 1 of 1 (back to results) methyl 5-aminolevulinate hydrochloride The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells.

Current search: 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > dermatologic drug [CHEBI:50177] > methyl 5-aminolevulinate hydrochloride [CHEBI:60641] × Select any link to see items in a related category. more general categories    information about this item 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  photosensitizing agent [CHEBI:47868] (22)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  dermatologic drug [CHEBI:50177] (49)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  prodrug [CHEBI:50266] (88)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   chlorine molecular entity [CHEBI:23117] (884)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic halide salt [CHEBI:51069] (386)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   methyl 5-aminolevulinate hydrochloride [CHEBI:60641] (1) ChEBI Compound Accession Identifier:   [CHEBI:60641] ChEBI Compound Description:   The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. ChEBI Compound Identification Number:   60641 ChEBI InChI Value:   "InChI=1S/C6H11NO3.ClH/c1-10-6(9)3-2-5(8)4-7;/h2-4,7H2,1H3;1H" ChEBI InChIKey Value:   UJYSYPVQHFNBML-UHFFFAOYSA-N ChEBI Compound Name:   methyl 5-aminolevulinate hydrochloride ChEBI SMILES Value:   [Cl-].COC(=O)CCC(=O)C[NH3+] ChEBI Substance ID:   103158555 ChEBI URL:   ChEBI:60641 ChemSpider ID:   138949 Ontomatica Chemical Accession Key (OnChAKey):   UJYSYPVQHFNBML_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   3036828