Item 1 of 1 (back to results) midodrine An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Current search: 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > prodrug [CHEBI:50266] > midodrine [CHEBI:6933] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   adrenergic agent [CHEBI:37962] (143)   sympathomimetic agent [CHEBI:35524] (33)   midodrine [CHEBI:6933] (1)  adrenergic agonist [CHEBI:37886] (42)   alpha-adrenergic agonist [CHEBI:35569] (17)   midodrine [CHEBI:6933] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   prodrug [CHEBI:50266] (88)   midodrine [CHEBI:6933] (1)  cardiovascular drug [CHEBI:35554] (162)   vasoconstrictor agent [CHEBI:50514] (29)   midodrine [CHEBI:6933] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   midodrine [CHEBI:6933] (1)  p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   amide [CHEBI:32988] (1863)   primary amide [CHEBI:33256] (1586)   carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   midodrine [CHEBI:6933] (1)  organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   ether [CHEBI:25698] (876)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  carboxamide [CHEBI:37622] (1381)   amino acid amide [CHEBI:22475] (23)   midodrine [CHEBI:6933] (1)  organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   midodrine [CHEBI:6933] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   aromatic compound [CHEBI:33655] (3799)   organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic aromatic compound [CHEBI:33659] (3593)   aromatic ether [CHEBI:35618] (353)   midodrine [CHEBI:6933] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   secondary alcohol [CHEBI:35681] (342)   midodrine [CHEBI:6933] (1) ChEBI Compound Accession Identifier:   [CHEBI:6933] ChEBI Compound Description:   An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. ChEBI Compound Identification Number:   6933 ChEBI InChI Value:   InChI=1S/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16) ChEBI InChIKey Value:   PTKSEFOSCHHMPD-UHFFFAOYSA-N ChEBI Compound Name:   midodrine ChEBI SMILES Value:   COc1ccc(OC)c(c1)C(O)CNC(=O)CN ChEBI Substance ID:   56464179 ChEBI URL:   ChEBI:6933 ChemSpider ID:   21238839 Ontomatica Chemical Accession Key (OnChAKey):   PTKSEFOSCHHMPD_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   4195