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1-hydroxy-5-phenyl-3-pentanone
A beta-hydroxy ketone that is pentan-3-one with a hydroxy group at position 1 and a phenyl group at position 5. Isolated from the edible mushroom Mycoleptodonoides aitchisonii, it exhibits protective activity against endoplasmic reticulum (ER) stress-dependent cell death.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > protective agent [CHEBI:50267] > neuroprotective agent [CHEBI:63726] > 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 protective agent [CHEBI:50267] (74) 
 neuroprotective agent [CHEBI:63726] (30) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 primary alcohol [CHEBI:15734] (167) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 primary alcohol [CHEBI:15734] (167) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 beta-hydroxy ketone [CHEBI:55380] (18) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 beta-hydroxy ketone [CHEBI:55380] (18) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 beta-hydroxy ketone [CHEBI:55380] (18) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 primary alcohol [CHEBI:15734] (167) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 beta-hydroxy ketone [CHEBI:55380] (18) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 organic molecule [CHEBI:72695] (11399) 
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 beta-hydroxy ketone [CHEBI:55380] (18) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 primary alcohol [CHEBI:15734] (167) 
 1-hydroxy-5-phenyl-3-pentanone [CHEBI:66037] (1)
ChEBI Compound Accession Identifier  [CHEBI:66037]
ChEBI Compound Description  A beta-hydroxy ketone that is pentan-3-one with a hydroxy group at position 1 and a phenyl group at position 5. Isolated from the edible mushroom Mycoleptodonoides aitchisonii, it exhibits protective activity against endoplasmic reticulum (ER) stress-dependent cell death.
ChEBI Compound Identification Number  66037
ChEBI InChI Value  InChI=1S/C11H14O2/c12-9-8-11(13)7-6-10-4-2-1-3-5-10/h1-5,12H,6-9H2
ChEBI InChIKey Value  VQTZONPDOFOTIF-UHFFFAOYSA-N
ChEBI Compound Name  1-hydroxy-5-phenyl-3-pentanone
ChEBI SMILES Value  OCCC(=O)CCc1ccccc1
ChEBI Substance ID  160709734
ChEBI URL  ChEBI:66037
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  VQTZONPDOFOTIF_UHFFFAOYSA_N_000_000000
PubChem Compound ID  15316212