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disodium clodronate tetrahydrate
The tetrahydrate of the disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > bone density conservation agent [CHEBI:50646] > disodium clodronate tetrahydrate [CHEBI:59587]
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05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 bone density conservation agent [CHEBI:50646] (18) 
 disodium clodronate tetrahydrate [CHEBI:59587] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 one-carbon compound [CHEBI:64708] (104) 
 disodium clodronate tetrahydrate [CHEBI:59587] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 addition compound [CHEBI:35504] (113) 
 hydrate [CHEBI:35505] (111) 
 disodium clodronate tetrahydrate [CHEBI:59587] (1)
ChEBI Compound Accession Identifier  [CHEBI:59587]
ChEBI Compound Description  The tetrahydrate of the disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.
ChEBI Compound Identification Number  59587
ChEBI InChI Value  "InChI=1S/CH4Cl2O6P2.2Na.4H2O/c2-1(3,10(4,5)6)11(7,8)9;;;;;;/h(H2,4,5,6)(H2,7,8,9);;;4*1H2/q;2*+1;;;;/p-2"
ChEBI InChIKey Value  XWHPUCFOTRBMGS-UHFFFAOYSA-L
ChEBI Compound Name  disodium clodronate tetrahydrate
ChEBI SMILES Value  O.O.O.O.[Na+].[Na+].OP([O-])(=O)C(Cl)(Cl)P(O)([O-])=O
ChEBI Substance ID  96079684
ChEBI URL  ChEBI:59587
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  XWHPUCFOTRBMGS_UHFFFAOYSA_L_000_000000
PubChem Compound ID  23724874