Item 1 of 1 (back to results) (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride A hydrochloride salt obtained by mixing equimolar amounts of (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol with hydrochloric acid. Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo.

Current search: 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > antidyskinesia agent [CHEBI:66956] > antiparkinson drug [CHEBI:48407] > (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   dopaminergic agent [CHEBI:48560] (99)   dopamine agonist [CHEBI:51065] (26)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antidyskinesia agent [CHEBI:66956] (43)   antiparkinson drug [CHEBI:48407] (41)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   chlorine molecular entity [CHEBI:23117] (884)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   salt [CHEBI:24866] (931)   organic salt [CHEBI:24868] (775)   organic halide salt [CHEBI:51069] (386)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1)  halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1)  halide [CHEBI:37578] (1402)   halide salt [CHEBI:33958] (423)   chloride salt [CHEBI:23114] (326)   organic chloride salt [CHEBI:36094] (294)   hydrochloride [CHEBI:36807] (240)   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride [CHEBI:64078] (1) ChEBI Compound Accession Identifier:   [CHEBI:64078] ChEBI Compound Description:   A hydrochloride salt obtained by mixing equimolar amounts of (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol with hydrochloric acid. Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. ChEBI Compound Identification Number:   64078 ChEBI InChI Value:   "InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1" ChEBI InChIKey Value:   BWHPNJVKFAPVOG-QYFJGNGUSA-N ChEBI Compound Name:   (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride ChEBI SMILES Value:   Cl.NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C12CC3CC(CC(C3)C1)C2 ChEBI Substance ID:   135610882 ChEBI URL:   ChEBI:64078 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   BWHPNJVKFAPVOG_QYFJGNGUSA_N_000_000000 PubChem Compound ID:   9951033