Item 1 of 1 (back to results) travoprost "The isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the cornea to the biologically active free acid, fluprostenol."

Current search: 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > ophthalmology drug [CHEBI:66981] > antiglaucoma drug [CHEBI:39456] > travoprost [CHEBI:746859] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   agonist [CHEBI:48705] (68)   prostaglandin receptor agonist [CHEBI:66900] (3)   travoprost [CHEBI:746859] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antihypertensive agent [CHEBI:35674] (104)   travoprost [CHEBI:746859] (1)  prodrug [CHEBI:50266] (88)   travoprost [CHEBI:746859] (1)  ophthalmology drug [CHEBI:66981] (30)   travoprost [CHEBI:746859] (1)  antiglaucoma drug [CHEBI:39456] (28)   travoprost [CHEBI:746859] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   fluorine molecular entity [CHEBI:24062] (288)   organofluorine compound [CHEBI:37143] (275)   travoprost [CHEBI:746859] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   travoprost [CHEBI:746859] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   travoprost [CHEBI:746859] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  ester [CHEBI:35701] (3370)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  fatty acid derivative [CHEBI:61697] (144)   icosanoid [CHEBI:23899] (138)   prostanoid [CHEBI:26347] (63)   prostaglandin [CHEBI:26333] (47)   prostaglandins F [CHEBI:26340] (20)   prostaglandins Falpha [CHEBI:36066] (18)   travoprost [CHEBI:746859] (1)  organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   travoprost [CHEBI:746859] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   travoprost [CHEBI:746859] (1) ChEBI Compound Accession Identifier:   [CHEBI:746859] ChEBI Compound Description:   "The isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the cornea to the biologically active free acid, fluprostenol." ChEBI Compound Identification Number:   746859 ChEBI InChI Value:   InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1 ChEBI InChIKey Value:   MKPLKVHSHYCHOC-AHTXBMBWSA-N ChEBI Compound Name:   travoprost ChEBI SMILES Value:   CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1cccc(c1)C(F)(F)F ChEBI Substance ID:   99367288 ChEBI URL:   ChEBI:746859 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   MKPLKVHSHYCHOC_AHTXBMBWSA_N_000_000000 PubChem Compound ID:   5282226