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dihydroergotamine mesylate
The methanesulfonic acid salt of dihydroergotamine, a semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine. Both the mesylate and the tartrate salts are used for the treatment of migraine and orthostatic hypotension.


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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 analgesic [CHEBI:35480] (114) 
 non-narcotic analgesic [CHEBI:35481] (56) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
 neurotransmitter agent [CHEBI:35942] (471) 
 serotonergic drug [CHEBI:48278] (109) 
 serotonergic agonist [CHEBI:35941] (41) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 cardiovascular drug [CHEBI:35554] (162) 
 vasoconstrictor agent [CHEBI:50514] (29) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 sulfur molecular entity [CHEBI:26835] (1541) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 methanesulfonates [CHEBI:48544] (33) 
 methanesulfonate salt [CHEBI:38037] (28) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organosulfonate salt [CHEBI:64382] (37) 
 methanesulfonate salt [CHEBI:38037] (28) 
 dihydroergotamine mesylate [CHEBI:59756] (1)
ChEBI Compound Accession Identifier  [CHEBI:59756]
ChEBI Compound Description  The methanesulfonic acid salt of dihydroergotamine, a semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine. Both the mesylate and the tartrate salts are used for the treatment of migraine and orthostatic hypotension.
ChEBI Compound Identification Number  59756
ChEBI InChI Value  "InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23-,25-,26+,27+,32-,33+;/m1./s1"
ChEBI InChIKey Value  ADYPXRFPBQGGAH-UMYZUSPBSA-N
ChEBI Compound Name  dihydroergotamine mesylate
ChEBI SMILES Value  CS(O)(=O)=O.[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@H](CN2C)C(=O)N[C@]1(C)O[C@]2(O)N([C@@H](Cc3ccccc3)C(=O)N3CCC[C@@]23[H])C1=O
ChEBI Substance ID  99319616
ChEBI URL  ChEBI:59756
ChemSpider ID  64311
Ontomatica Chemical Accession Key (OnChAKey)  ADYPXRFPBQGGAH_UMYZUSPBSA_N_000_000000
PubChem Compound ID  71171