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ergometrine maleate
The maleic acid salt of ergometrine, an ergot alkaloid that has a particularly powerful action on the uterus. It is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by maintaining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced. It has also been used in the diagnosis of oesophageal spasm, and in a provocation test for the diagnosis of Prinzmetal's angina.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > diagnostic agent [CHEBI:33295] > ergometrine maleate [CHEBI:31554]
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05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 oxytocic [CHEBI:36063] (8) 
 ergometrine maleate [CHEBI:31554] (1)
 diagnostic agent [CHEBI:33295] (53) 
 ergometrine maleate [CHEBI:31554] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 maleate salt [CHEBI:50221] (31) 
 ergometrine maleate [CHEBI:31554] (1)
ChEBI Compound Accession Identifier  [CHEBI:31554]
ChEBI Compound Description  The maleic acid salt of ergometrine, an ergot alkaloid that has a particularly powerful action on the uterus. It is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by maintaining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced. It has also been used in the diagnosis of oesophageal spasm, and in a provocation test for the diagnosis of Prinzmetal's angina.
ChEBI Compound Identification Number  31554
ChEBI InChI Value  "InChI=1S/C19H23N3O2.C4H4O4/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;5-3(6)1-2-4(7)8/h3-6,8,11,13,17,20,23H,7,9-10H2,1-2H3,(H,21,24);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11-,13+,17+;/m0./s1"
ChEBI InChIKey Value  YREISLCRUMOYAY-IIPCNOPRSA-N
ChEBI Compound Name  ergometrine maleate
ChEBI SMILES Value  OC(=O)\C=C/C(O)=O.[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N[C@@H](C)CO)c34
ChEBI Substance ID  99319116
ChEBI URL  ChEBI:31554
ChemSpider ID  4941654
Ontomatica Chemical Accession Key (OnChAKey)  YREISLCRUMOYAY_IIPCNOPRSA_N_000_000000
PubChem Compound ID  6437065