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edrophonium chloride
The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > protective agent [CHEBI:50267]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 cholinesterase inhibitor [CHEBI:37733] (52) 
 edrophonium chloride [CHEBI:4759] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 protective agent [CHEBI:50267] (74) 
 antidote [CHEBI:50247] (10) 
 edrophonium chloride [CHEBI:4759] (1)
 diagnostic agent [CHEBI:33295] (53) 
 edrophonium chloride [CHEBI:4759] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 halogen molecular entity [CHEBI:24471] (1475) 
 chlorine molecular entity [CHEBI:23117] (884) 
 chloride salt [CHEBI:23114] (326) 
 edrophonium chloride [CHEBI:4759] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 edrophonium chloride [CHEBI:4759] (1)
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 quaternary nitrogen compound [CHEBI:26469] (238) 
 quaternary ammonium salt [CHEBI:35273] (50) 
 edrophonium chloride [CHEBI:4759] (1)
 ammonium compound [CHEBI:35276] (129) 
 organoammonium salt [CHEBI:46850] (104) 
 quaternary ammonium salt [CHEBI:35273] (50) 
 edrophonium chloride [CHEBI:4759] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 edrophonium chloride [CHEBI:4759] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 edrophonium chloride [CHEBI:4759] (1)
ChEBI Compound Accession Identifier  [CHEBI:4759]
ChEBI Compound Description  The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
ChEBI Compound Identification Number  4759
ChEBI InChI Value  "InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H"
ChEBI InChIKey Value  BXKDSDJJOVIHMX-UHFFFAOYSA-N
ChEBI Compound Name  edrophonium chloride
ChEBI SMILES Value  [Cl-].CC[N+](C)(C)c1cccc(O)c1
ChEBI Substance ID  99313638
ChEBI URL  ChEBI:4759
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  BXKDSDJJOVIHMX_UHFFFAOYSA_N_000_000000
PubChem Compound ID  8307