Item 1 of 1 (back to results) metachromin S A sesquiterpenoid that is 5-amino-2-hydroxy-3-methyl-1,4-benzoquinone in which one of the hydrogens of the methyl group is replaced by a 2-methyl-4-[(1R,2S)-1,2,3-trimethylcyclohex-3-en-1-yl]but-1-en-1-yl group and one of the hydrogens attached to the nitrogen is replaced by a 3-methylbutyl group. It is isolated from an Okinawan sponge Spongia sp.SS-1037 and exhibits moderate cytotoxicity against L1210 murine leukemia and KB human epidermoid carcinoma cells.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > antineoplastic agent [CHEBI:35610] > metachromin S [CHEBI:66695] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   metachromin S [CHEBI:66695] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   metachromin S [CHEBI:66695] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Animalia (46)   Porifera (33)   Demospongiae (33)   Dictyoceratida (3)   Spongiidae (3)   Spongia (3) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  unspecified structure [PO:0000004] (703) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   metachromin S [CHEBI:66695] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   sesquiterpenoid [CHEBI:26658] (209)   metachromin S [CHEBI:66695] (1)  isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   sesquiterpenoid [CHEBI:26658] (209)   metachromin S [CHEBI:66695] (1)  heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   metachromin S [CHEBI:66695] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  organic amino compound [CHEBI:50047] (2472)   secondary amino compound [CHEBI:50995] (110)   metachromin S [CHEBI:66695] (1)  organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   ketone [CHEBI:17087] (1288)   cyclic ketone [CHEBI:3992] (644)   quinone [CHEBI:36141] (209)   benzoquinones [CHEBI:22729] (30)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   2-hydroxy-1,4-benzoquinones [CHEBI:67273] (3)   metachromin S [CHEBI:66695] (1) ChEBI Compound Accession Identifier:   [CHEBI:66695] ChEBI Compound Description:   A sesquiterpenoid that is 5-amino-2-hydroxy-3-methyl-1,4-benzoquinone in which one of the hydrogens of the methyl group is replaced by a 2-methyl-4-[(1R,2S)-1,2,3-trimethylcyclohex-3-en-1-yl]but-1-en-1-yl group and one of the hydrogens attached to the nitrogen is replaced by a 3-methylbutyl group. It is isolated from an Okinawan sponge Spongia sp.SS-1037 and exhibits moderate cytotoxicity against L1210 murine leukemia and KB human epidermoid carcinoma cells. ChEBI Compound Identification Number:   66695 ChEBI InChI Value:   InChI=1S/C26H39NO3/c1-17(2)12-15-27-22-16-23(28)25(30)21(24(22)29)10-9-18(3)11-14-26(6)13-7-8-19(4)20(26)5/h8-9,16-17,20,27,30H,7,10-15H2,1-6H3/b18-9+/t20-,26-/m1/s1 ChEBI InChIKey Value:   YBVKKXUZRPNHQO-JEJCENLRSA-N ChEBI Compound Name:   metachromin S ChEBI SMILES Value:   CC(C)CCNC1=CC(=O)C(O)=C(C\C=C(/C)CC[C@@]2(C)CCC=C(C)[C@H]2C)C1=O ChEBI Substance ID:   160645533 ChEBI URL:   ChEBI:66695 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   YBVKKXUZRPNHQO_JEJCENLRSA_N_000_000000 PubChem Compound ID:   25053703